catalog number :
MBS129611
products full name :
BLVRA Polyclonal Antibody
products short name :
[BLVRA]
products name syn :
[BVR; BLVR; BVRA]
other names :
[Biliverdin reductase A; Biliverdin reductase A; biliverdin reductase A; BVR A; biliverdin-IX alpha-reductase; biliverdin reductase A; Biliverdin-IX alpha-reductase]
products gene name :
[BLVRA]
other gene names :
[BLVRA; BLVRA; BVR; BLVR; BVRA; BLVR; BVR; BVR A]
uniprot entry name :
BIEA_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Category: Primary antibody. Species: Human
other info2 :
Immunogen: Recombinant protein of human BLVRA. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene.
ncbi pathways :
Heme Degradation Pathway (160971); Metabolism Pathway (477135); Metabolism Of Porphyrins Pathway (106325); Porphyrin And Chlorophyll Metabolism Pathway (83021); Porphyrin And Chlorophyll Metabolism Pathway (407); Heme Degradation Pathway (545346); Heme Degradation Pathway (139483)
ncbi summary :
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
BVR: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Monomer. Liver. Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. Protein type: Oxidoreductase; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.1.24; ATYPICAL group; BLVRA family. Chromosomal Location of Human Ortholog: 7p13. Cellular Component: cytosol. Molecular Function: zinc ion binding; biliverdin reductase activity. Biological Process: heme catabolic process; porphyrin metabolic process. Disease: Hyperbiliverdinemia