antibody

IL3RA Polyclonal Antibody

MBS129602

0.05 mL

200 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry

Antibody

IL3RA Polyclonal Antibody

[IL3RA]

[IL3RA; CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin-3 receptor subunit alpha]

[Interleukin-3 receptor subunit alpha; Interleukin-3 receptor subunit alpha; interleukin-3 receptor subunit alpha; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; interleukin 3 receptor, alpha (low affinity); CD_antigen: CD123]

[IL3RA]

[IL3RA; IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA]

IL3RA_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

378

Affinity Purification

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB), Immunohistochemistry (IHC)

WB: 1:500-1:2000. IHC: 1:100 - 1:200

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)

Immunogen: A synthetic peptide corresponding toa sequence within amino acids 1-100 of human IL3RA (NP_002174.1).

Polyclonal

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

417184

NP_002174.1

P26951

Observed MW: 70kDa. Calculated MW: 34kDa/43kDa

Apoptosis Pathway (83060); Apoptosis Pathway (470); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); G Beta:gamma Signalling Through PI3Kgamma Pathway (119540); G-protein Beta:gamma Signalling Pathway (119539); GPCR Downstream Signaling Pathway (119548); GPVI-mediated Activation Cascade Pathway (106036); Hematopoietic Cell Lineage Pathway (83078)

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]

IL3RA: This is a receptor for interleukin-3. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3. Cellular Component: plasma membrane; integral to membrane. Molecular Function: interleukin-3 receptor activity

0.05 mL

200 USD

0.1 mL

275

0.2 mL

430