product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Endothelial protein C receptor (PROCR)
catalog :
MBS1294466
quantity :
0.5 mg (E-Coli)
price :
940 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1294466
products type :
Recombinant Protein
products full name :
Recombinant Human Endothelial protein C receptor (PROCR)
products short name :
Endothelial protein C receptor (PROCR)
products name syn :
Endothelial protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen=; CD201
other names :
endothelial protein C receptor; Endothelial protein C receptor; endothelial protein C receptor; APC receptor; centrocyclin; CD201 antigen; activated protein C receptor; cell cycle, centrosome-associated protein; protein C receptor, endothelial; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
products gene name :
PROCR
products gene name syn :
PROCR; EPCR
other gene names :
PROCR; PROCR; CCCA; EPCR; CCD41; EPCR; APC receptor
uniprot entry name :
EPCR_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
18-210
sequence length :
193
sequence :
SQD ASDGLQRLHM LQISYFRDPY HVWYQGNASL GGHLTHVLEG PDTNTTIIQL QPLQEPESWA RTQSGLQSYL LQFHGLVRLV HQERTLAFPL TIRCFLGCEL PPEGSRAHVF FEVAVNGSSF VSFRPERALW QADTQVTSGV VTFTLQQLNA YNRTRYELRE FLEDTCVQYV QKHISAENTK GSQTSRSYTS
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
ncbi gi num :
34335272
ncbi acc num :
NP_006395.2
ncbi gb acc num :
NM_006404.4
uniprot acc num :
Q9UNN8
ncbi mol weight :
22kD
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
ncbi summary :
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
uniprot summary :
EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 20q11.2. Cellular Component: centrosome; cell surface; focal adhesion; integral to plasma membrane; plasma membrane; extracellular region. Molecular Function: protein binding; receptor activity. Biological Process: antigen processing and presentation; immune response; negative regulation of coagulation; blood coagulation; leukocyte migration
size1 :
0.5 mg (E-Coli)
price1 :
940 USD
size2 :
0.05 mg (Baculovirus)
price2 :
940
size3 :
0.5 mg (Yeast)
price3 :
1165
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1165
size5 :
1 mg (E-Coli)
price5 :
1400
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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