catalog number :
MBS129381
products full name :
SLC39A6 Polyclonal Antibody
products short name :
[SLC39A6]
products name syn :
[LIV-1;ZIP6]
other names :
[Zinc transporter ZIP6; Zinc transporter ZIP6; zinc transporter ZIP6; ZIP-6; zrt- and Irt-like protein 6; estrogen-regulated protein LIV-1; LIV-1 protein, estrogen regulated; solute carrier family 39 member 6; solute carrier family 39 (metal ion transporter), member 6; solute carrier family 39 (zinc transporter), member 6; Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6]
products gene name :
[SLC39A6]
other gene names :
[SLC39A6; SLC39A6; LIV-1; LIV1; ZIP6; ZIP-6]
uniprot entry name :
S39A6_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-320 of human SLC39A6 (NP_001092876.1). Species: Human. Immunogen: Recombinant Protein. Category: Polyclonal Antibodies. Observed MW: 102kDa. Calculated MW: 48kDa/85kDa
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003
ncbi pathways :
Metal Ion SLC Transporters Pathway (161066); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571); Zinc Influx Into Cells By The SLC39 Gene Family Pathway (161069); Zinc Transporters Pathway (161067)
ncbi summary :
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
uniprot summary :
SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter. Chromosomal Location of Human Ortholog: 18q12.2. Cellular Component: cell surface; integral to plasma membrane; endoplasmic reticulum; plasma membrane. Molecular Function: zinc ion transmembrane transporter activity. Biological Process: cellular zinc ion homeostasis; transmembrane transport