catalog number :
MBS129128
products full name :
UPK2 Polyclonal Antibody
products short name :
UPK2
products name syn :
UP2; UPII
other names :
Uroplakin-2; Uroplakin-2; uroplakin-2; uroplakin II; uroplakin 2; Uroplakin II; UPII
products gene name :
UPK2
other gene names :
UPK2; UPK2; UP2; UPII; UP2; UPII
uniprot entry name :
UPK2_HUMAN
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:200 - 1:2000
other info1 :
Cross reactivity: Rat, Mouse. Immunogen: a synthetic peptide of human UPK2. Calculated Molecular Weight: 19kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
other info2 :
Immunogen: a synthetic peptide of human UPK2. Calculated Molecular Weight: 19kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.
ncbi summary :
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
uniprot summary :
UPK2: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. Belongs to the uroplakin-2 family. Protein type: Membrane protein, integral; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 11q23. Cellular Component: integral to plasma membrane; apical plasma membrane; integral to endoplasmic reticulum membrane. Biological Process: epithelial cell differentiation; multicellular organismal development