product summary
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company name :
MyBioSource
product type :
antibody
product name :
CDK2AP1 Polyclonal Antibody
catalog :
MBS128985
quantity :
0.05 mL
price :
285 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
catalog number :
MBS128985
products type :
Antibody
products full name :
CDK2AP1 Polyclonal Antibody
products short name :
CDK2AP1
products name syn :
DOC1; ST19; DORC1; doc-1; p12DOC-1
other names :
Cyclin-dependent kinase 2-associated protein 1; Cyclin-dependent kinase 2-associated protein 1; cyclin-dependent kinase 2-associated protein 1; Deleted in oral cancer-1; deleted in oral cancer 1; CDK2-associated protein 1; putative oral cancer suppressor; cyclin-dependent kinase 2 associated protein 1; Deleted in oral cancer 1; DOC-1; Putative oral cancer suppressor
products gene name :
CDK2AP1
other gene names :
CDK2AP1; CDK2AP1; DOC1; ST19; DORC1; doc-1; p12DOC-1; CDKAP1; DOC1; CDK2-associated protein 1; DOC-1
uniprot entry name :
CDKA1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
115
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB)
app notes :
WB: 1:200 - 1:1000
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human CDK2AP1. Calculated Molecular Weight: 13kDa
products categories :
Polyclonal
products description :
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
ncbi gi num :
6014988
ncbi acc num :
O14519.1
uniprot acc num :
O14519
ncbi mol weight :
115
ncbi summary :
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
uniprot summary :
CDK2AP1: specific inhibitor of the cell-cycle kinase CDK2. Belongs to the CDK2AP family. Protein type: DNA replication; Tumor suppressor; Cell cycle regulation. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: perinuclear region of cytoplasm; nucleus. Biological Process: positive regulation of protein amino acid phosphorylation; DNA-dependent DNA replication; cell cycle
size1 :
0.05 mL
price1 :
285 USD
size2 :
0.2 mL
price2 :
555
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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