product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Reston ebolavirus Polymerase cofactor VP35 (VP35)
catalog :
MBS1288129
quantity :
0.5 mg (E-Coli)
price :
1090 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1288129
products type :
Recombinant Protein
products full name :
Recombinant Reston ebolavirus Polymerase cofactor VP35 (VP35)
products short name :
Polymerase cofactor VP35 (VP35)
products name syn :
Polymerase cofactor VP35
other names :
Polymerase cofactor VP35; Polymerase cofactor VP35
products gene name :
VP35
other gene names :
VP35
uniprot entry name :
VP35_EBORE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-329
sequence length :
329
sequence :
MYNDKLKICS GPETTGWISE QLMTGKIPVT DIFIDIDNKP DQMEVRLKPS SRSSTRTCTS SSQTEVNYVP LLKKVEDTLT MLVSATSRQN AAIEALENRL STLESSLKPI QDMGKVISSL NRSCAEMVAK YDLLVMTTGR ATSTAAAVDA YWKEHKQPPP GPALYEENAL KGKIDDPNSY VPDAVQEAYK NLDSTSTLTE ENFGKPYISA KDLKEIMYDH LPGFGTAFHQ LVQVICKIGK DNNLLDTIHA EFQASLADGD SPQCALIQIT KRVPIFQDVP PPTIHIRSRG DIPRACQKSL RPAPPSPKID RGWVCLFKMQ DGKTLGLKI
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Reston ebolavirus (strain Philippines-96) (REBOV) (Reston Ebola virus)
products description :
Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex. Prevents establishment of cellular antiviral state by blocking virus-induced phosphorylation and activation of interferon regulatory factor 3 (IRF3), a transcription factor critical for the induction of interferons alpha and beta. This blockage is produced through the interaction with and inhibition host IKBKE and TBK1 producing a strong inhibition of the phosphorylation and activation of IRF3. Also inhibits the antiviral effect mediated by the interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR (By similarity).
ncbi gi num :
81961765
ncbi acc num :
Q91DE0.1
uniprot acc num :
Q91DE0
ncbi mol weight :
51kD
size1 :
0.5 mg (E-Coli)
price1 :
1090 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1090
size3 :
0.5 mg (Yeast)
price3 :
1320
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1320
size5 :
1 mg (E-Coli)
price5 :
1715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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