product summary
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company name :
MyBioSource
product type :
antibody
product name :
PPP3CB Polyclonal Antibody
catalog :
MBS128626
quantity :
0.05 mL
price :
285 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
product information
catalog number :
MBS128626
products type :
Antibody
products full name :
PPP3CB Polyclonal Antibody
products short name :
PPP3CB
products name syn :
CNA2; CALNB; CALNA2; PP2Bbeta
other names :
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; calcineurin A2; calcineurin A beta; CAM-PRP catalytic subunit; protein phosphatase from PCR fragment H32; calmodulin-dependent calcineurin A subunit beta isoform; protein phosphatase 2B, catalytic subunit, beta isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit beta isoform
products gene name :
PPP3CB
other gene names :
PPP3CB; PPP3CB; CNA2; CALNB; CALNA2; PP2Bbeta; CALNA2; CALNB; CNA2
uniprot entry name :
PP2BB_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
524
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
other info1 :
Species: Human. Route: Synthetic Peptide
other info2 :
Immunogen: A synthetic peptide of human PPP3CB. Calculated Molecular Weight: 59kDa
products categories :
Polyclonal
products description :
PPP3CB (protein phosphatase 3, catalytic subunit, beta isozyme) is a protein-coding gene. GO annotations related to this gene include calmodulin binding and calcium ion binding. An important paralog of this gene is PPP3CA.
ncbi gi num :
60659599
ncbi acc num :
P16298.2
uniprot acc num :
P16298
ncbi mol weight :
524
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (920975); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (83060); Apoptosis Pathway (470)
uniprot summary :
PPP3CB: a calmodulin-dependent Ser/Thr phosphatase also known calcineurin A beta. Involved in a wide range of biologic activities, acting as a Ca(2 )-dependent modifier of phosphorylation status. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor). Chromosomal Location of Human Ortholog: 10q22.2. Cellular Component: nucleoplasm; T-tubule; plasma membrane; Z disc; cytosol; calcineurin complex. Molecular Function: protein dimerization activity; calmodulin binding; protein binding; enzyme binding; calmodulin-dependent protein phosphatase activity; calcium ion binding; protein serine/threonine phosphatase activity; drug binding; protein phosphatase 2B binding. Biological Process: T cell activation; positive regulation of NFAT protein import into nucleus; axon extension; heart development; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; learning; social behavior; signal transduction; protein amino acid dephosphorylation; protein amino acid phosphorylation; memory; calcium ion-dependent exocytosis; locomotion during locomotory behavior; T cell proliferation; calcineurin-NFAT signaling pathway; dephosphorylation; response to cytokine stimulus; negative regulation of T cell mediated cytotoxicity; innate immune response; T cell homeostasis; positive regulation of transcription from RNA polymerase II promoter; regulation of insulin secretion; T cell differentiation
size1 :
0.05 mL
price1 :
285 USD
size2 :
0.2 mL
price2 :
555
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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