product summary
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company name :
MyBioSource
product type :
antibody
product name :
SSTR5 Polyclonal Antibody
catalog :
MBS128105
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of extracts of HT-29 cells, using SSTR5 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS128105
products type :
Antibody
products full name :
SSTR5 Polyclonal Antibody
products short name :
[SSTR5]
products name syn :
[SS-5-R]
other names :
[Somatostatin receptor type 5; Somatostatin receptor type 5; somatostatin receptor type 5; somatostatin receptor subtype 5; somatostatin receptor 5]
products gene name :
[SSTR5]
other gene names :
[SSTR5; SSTR5; SS-5-R; SS-5-R; SS5-R; SS5R]
uniprot entry name :
SSR5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
364
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Calculated MW: 39 kDa. Observed MW: 50 kDa. Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 275-364 of human SSTR5 (NP_001044.1). Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
ncbi gi num :
12644225
ncbi acc num :
P35346.3
uniprot acc num :
P35346
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)
ncbi summary :
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]
uniprot summary :
SSTR5: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; GPCR, family 1; Cell cycle regulation; Receptor, GPCR; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: neuron projection; integral to plasma membrane; plasma membrane. Molecular Function: neuropeptide binding; somatostatin receptor activity. Biological Process: positive regulation of cytokinesis; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; glucose homeostasis; regulation of insulin secretion. Disease: Pituitary Adenoma, Growth Hormone-secreting
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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