product summary
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company name :
MyBioSource
product type :
antibody
product name :
PTGIR Polyclonal Antibody
catalog :
MBS127986
quantity :
0.05 mL
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS127986
products type :
Antibody
products full name :
PTGIR Polyclonal Antibody
products short name :
PTGIR
products name syn :
IP; PRIPR
other names :
Prostacyclin receptor; Prostacyclin receptor; prostacyclin receptor; PGI receptor; PGI2 receptor; prostanoid IP receptor; prostaglandin I2 receptor; prostaglandin I2 (prostacyclin) receptor (IP); Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor
products gene name :
PTGIR
other gene names :
PTGIR; PTGIR; IP; PRIPR; PRIPR; PGI receptor; PGI2 receptor
uniprot entry name :
PI2R_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
386
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human PTGIR. Calculated Molecular Weight: 40kDa
products categories :
Polyclonal
products description :
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
ncbi gi num :
1172500
ncbi acc num :
P43119.1
uniprot acc num :
P43119
ncbi mol weight :
386
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); Eicosanoid Ligand-binding Receptors Pathway (106370); Endothelin Pathway (672453); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Hemostasis Pathway (106028)
ncbi summary :
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
PTGIR: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: integral to plasma membrane; plasma membrane; cytosol. Molecular Function: G-protein coupled receptor activity; guanyl-nucleotide exchange factor activity. Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; negative regulation of smooth muscle cell proliferation; positive regulation of cAMP biosynthetic process; response to lipopolysaccharide; blood coagulation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of GTPase activity
size1 :
0.05 mL
price1 :
230 USD
size2 :
0.1 mL
price2 :
305
size3 :
0.2 mL
price3 :
460
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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