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company name :
MyBioSource
product type :
cDNA
product name :
LTF cDNA Clone
catalog :
MBS1278850
quantity :
0.01 mg Plasmid + 0.
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1278850
products type :
cDNA Clone
products full name :
LTF cDNA Clone
products short name :
LTF
other names :
Homo sapiens lactotransferrin, mRNA; Lactotransferrin; lactotransferrin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; lactotransferrin; Growth-inhibiting protein 12; Talalactoferrin
products gene name :
LTF
other gene names :
LTF; LTF; LF; HLF2; GIG12; GIG12; LF; Lactoferrin; Lfcin-H
uniprot entry name :
TRFL_HUMAN
sequence length :
2399
sequence :
atgaaacttgtcttcctcgtcctgctgttcctcggggcc
ctcggactgtgtctggctggcagtaggagaaggagtgtt
cagtggtgcgccgtatcccaacccgaggccacaaaatgc
ttccaatggcaaaggaatatgagaaaagtgcgtggccct
cctgtcagctgcataaagagagactcccccatccagtgt
atccaggccattgcggaaaacagggccgatgctgtgacc
cttgatggtggtttcatatacgaggcaggcctggccccc
tacaaactgcgacctgtagcggcggaagtctacgggacc
gaaagacagccacgaactcactattatgccgtggctgtg
gtgaagaagggcggcagctttcagctgaacgaactgcaa
tgtctgaagtcctgccacacaggccttcgcaggaccgct
ggatggaatgtccctatagggacacttcgtccattcttg
aattggacgggtccacctgagcccattgaggcagctgtg
gccaggttcttctcagccagctgtgttcccggtgcagat
aaaggacagttccccaacctgtgtcgcctgtgtgcgggg
acaggggaaaacaaatgtgccttctcctcccaggaaccg
tacttcagctactctggtgccttcaagtgtctgagagac
ggggctggagacgtggcttttatcagagagagcacagtg
tttgaggacctgtcagacgaggctgaaagggacgagtat
gagttactctgcccagacaacactcggaagccagtggac
aagttcaaagactgccatctggcccgggtcccttctcat
gccgttgtggcacgaagtgtgaatggcaaggaggatgcc
atctggaatcttctccgccaggcacaggaaaagtttgga
aaggacaagtcaccgaaattccagctctttggctcccct
agtgggcagaaagatctgctgttcaaggactctgccatt
gggttttcgagggtgcccccgaggatagattctgggctg
taccttggctccggctacttcactgccatccagaacttg
aggaaaagtgaggaggaagtggctgcccggcgtgcgcgg
gtcgtgtggtgtgcggtgggcgagcaggagctgcgcaag
tgtaaccagtggagtggcttgagcgaaggcagcgtgacc
tgctcctcggcctccaccacagaggactgcatcgccctg
gtgctgaaaggagaagctgatgccatgagtttggatgga
ggatatgtgtacactgcaggcaaatgtggtttggtgcct
gtcctggcagagaactacaaatcccaacaaagcagtgac
cctgatcctaactgtgtggatagacctgtggaaggatat
cttactgtggcggtggttaggagatcagacactagcctt
acctggaactctgtgaaaggcaagaagtcctgccacacc
gccgtggacaggactgcaggctggaatatccccatgggc
ctgctcttcaaccagacgggctcctgcaaatttgatgaa
tatttcagtcaaagctgtgcccctgggtctgacccgaga
tctaatctctgtgctctgtgtattggcgacgagcagggt
gagaataagtgcgtgcccaacagcaacgagagatactac
ggctacactggggctttccggtgcctggctgagaatgct
ggagacgttgcatttgtgaaagatgtcactgtcttgcag
aacactgatggaaataacaatgaggcatgggctaaggat
ttgaagctggcagactttgcgctgctgtgcctcgatggc
aaacggaagcctgtgactgaggctagaagctgccatctt
gccatggccccgaatcatgccgtggtgtctcggatggat
aaggtggaacgcctgaaacaggtgttgctccaccaacag
gctaaatttgggagaaatggatctgactgcccggacaag
ttttgcttattccagtctgaaaccaaaaaccttctgttc
aatgacaacactgagtgtctggccagactccatggcaaa
acaacatatgaaaaatatttggggccacagtatgtcgca
ggcattactaatctgaaaaagtgctcaacctcccccctc
ctggaagcctgtgaattcctcaggaagtaa
other info1 :
Vector: Please Inquire. Gene ID: 4057. Insert Site: rrnB_T1, rrnB_T2. cDNA Size: 2136
products description :
Homo sapiens lactotranferrin, mRNA(cDNA clone MGC:13619 IMAGE: 4294752). Complete cds.
ncbi gi num :
16198358
ncbi acc num :
BC015823
uniprot acc num :
P02788
ncbi mol weight :
78,182 Da
ncbi pathways :
Amyloids Pathway (366238); Disease Pathway (530764); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Mtb Iron Assimilation By Chelation Pathway (645273); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); Response Of Mtb To Phagocytosis Pathway (645269)
ncbi summary :
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
uniprot summary :
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule. Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; iron ion binding; serine-type endopeptidase activity. Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; retinal homeostasis; positive regulation of osteoblast differentiation; negative regulation of viral genome replication; innate immune response in mucosa; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of viral reproduction; negative regulation of ATPase activity; iron assimilation by chelation and transport; negative regulation of apoptosis
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
175 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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