catalog number :
MBS1278696
products type :
cDNA Clone
products full name :
DUSP13 cDNA Clone
products short name :
DUSP13
other names :
Homo sapiens dual specificity phosphatase 13, mRNA; Dual specificity protein phosphatase 13 isoform A; dual specificity protein phosphatase 13; dual specificity phosphatase 13; Branching-enzyme interacting DSP; Muscle-restricted DSP; MDSP
products gene name :
DUSP13
other gene names :
DUSP13; DUSP13; BEDP; MDSP; TMDP; SKRP4; DUSP13A; DUSP13B; BEDP; DUSP13A; MDSP; DUSP13A; MDSP
uniprot entry name :
DS13A_HUMAN
sequence :
atggactcactgcagaagcaggacctccggaggcccaag
atccatggggcagtccaggcatctccctaccagccgccc
acattggcttcgctgcagcgcttgctgtgggtccgtcag
gctgccacactgaaccatatcgatgaggtctggcccagc
ctcttcctgggagatgcgtacgcagcccgggacaagagc
aagctgatccagctgggaatcacccacgttgtgaatgcc
gctgcaggcaagttccaggtggacacaggtgccaaattc
taccgtggaatgtccctggagtactatggcatcgaggcg
gatgacaaccccttcttcgacctcagtgtctactttctg
cctgttgctcgatacatccgagctgccctcagtgttccc
caaggccgcgtgctggtacactgtgccatgggggtaagc
cgctctgccacacttgtcctggccttcctcatgatctat
gagaacatgacgctggtagaggccatccagacggtgcag
gcccaccgcaatatctgccctaactcaggcttcctccgg
cagctccaggttctggacaaccgactggggcgggagacg
gggcggttctga
other info1 :
Vector: Please Inquire
ncbi mol weight :
17,283 Da
ncbi summary :
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]
uniprot summary :
DUSP13 iso5: May be involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. Exhibits intrinsic phosphatase activity towards both phospho- seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 5 isoforms of the human protein are produced by alternative promoter. Protein type: EC 3.1.3.48; Cell cycle regulation; EC 3.1.3.16; Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q22.2. Molecular Function: phosphoric monoester hydrolase activity; protein binding. Biological Process: dephosphorylation; meiosis; protein amino acid dephosphorylation; spermatogenesis
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock