catalog number :
MBS1278627
products type :
cDNA Clone
products full name :
HIST1H1C cDNA Clone
products short name :
HIST1H1C
other names :
Homo sapiens histone cluster 1, H1c, mRNA; Histone H1.2; histone H1.2; histone cluster 1 H1 family member c; Histone H1c; Histone H1d; Histone H1s-1
products gene name :
HIST1H1C
other gene names :
HIST1H1C; HIST1H1C; H1C; H1.2; H1F2; H1s-1; H1F2
uniprot entry name :
H12_HUMAN
sequence :
atgtccgagactgctcctgccgctcccgctgccgcgcct
cctgcggagaaggcccctgtaaagaagaaggcggccaaa
aaggctgggggtacgcctcgtaaggcgtctggtcccccg
gtgtcagagctcatcaccaaggctgtggccgcctctaaa
gagcgtagcggagtttctctggctgctctgaaaaaagcg
ttggctgccgccggctatgatgtggagaaaaacaacagc
cgtatcaaacttggtctcaagagcctggtgagcaagggc
actctggtgcaaacgaaaggcaccggtgcttctggctcc
tttaaactcaacaagaaggcagcctccggggaagccaag
cccaaggttaaaaaggcgggcggaaccaaacctaagaag
ccagttggggcagccaagaagcccaagaaggcggctggc
ggcgcaactccgaagaagagcgctaagaaaacaccgaag
aaagcgaagaagccggccgcggccactgtaaccaagaaa
gtggctaagagcccaaagaaggccaaggttgcgaagccc
aagaaagctgccaaaagtgctgctaaggctgtgaagccc
aaggccgctaagcccaaggttgtcaagcctaagaaggcg
gcgcccaagaagaaatag
other info1 :
Vector: Please Inquire
ncbi mol weight :
21,365 Da
ncbi pathways :
Activation Of DNA Fragmentation Factor Pathway (105683); Apoptosis Pathway (105648); Apoptosis Induced DNA Fragmentation Pathway (105682); Apoptotic Execution Phase Pathway (105677)
ncbi summary :
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
uniprot summary :
H1C: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. Belongs to the histone H1/H5 family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: nucleus. Molecular Function: chromatin DNA binding; protein binding
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock