catalog number :
MBS127789
products full name :
RNASE3
products short name :
RNASE3
other names :
Eosinophil cationic protein; Eosinophil cationic protein; eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease; ribonuclease, RNase A family, 3; Ribonuclease 3; RNase 3
products gene name :
RNASE3
other gene names :
RNASE3; RNASE3; ECP; RNS3; ECP; RNS3; ECP; RNase 3
uniprot entry name :
ECP_HUMAN
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB:1:500-1:2000
other info1 :
Species: Human. Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human RNASE3
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
products categories :
Polyclonal
products description :
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria.
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532)
ncbi summary :
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
uniprot summary :
RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family. Protein type: Secreted; Secreted, signal peptide; EC 3.1.27.-; Ribonuclease. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular space; extracellular region. Molecular Function: nucleic acid binding; endonuclease activity; ribonuclease activity. Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response