product summary
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company name :
MyBioSource
product type :
cDNA
product name :
OTX2 cDNA Clone
catalog :
MBS1276989
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1276989
products type :
cDNA Clone
products full name :
OTX2 cDNA Clone
products short name :
OTX2
other names :
Homo sapiens orthodenticle homeobox 2, mRNA; Homeobox protein OTX2; homeobox protein OTX2; orthodenticle homeobox 2; Orthodenticle homolog 2
products gene name :
OTX2
other gene names :
OTX2; OTX2; CPHD6; MCOPS5
uniprot entry name :
OTX2_HUMAN
sequence length :
2220
sequence :
atgatgtcttatcttaagcaaccgccttacgcagtcaat
gggctgagtctgaccacttcgggtatggacttgctgcac
ccctccgtgggctacccggggccctgggcttcttgtccc
gcagccaccccccggaaacagcgccgggagaggacgacg
ttcactcgggcgcagctagatgtgctggaagcactgttt
gccaagacccggtacccagacatcttcatgcgagaggag
gtggcactgaaaatcaacttgcccgagtcgagggtgcag
gtatggtttaagaatcgaagagctaagtgccgccaacaa
cagcaacaacagcagaatggaggtcaaaacaaagtgaga
cctgccaaaaagaagacatctccagctcgggaagtgagt
tcagagagtggaacaagtggccaattcactcccccctct
agcacctcagtcccgaccattgccagcagcagtgctcct
gtgtctatctggagcccagcttccatctccccactgtca
gatcccttgtccacctcctcttcctgcatgcagaggtcc
tatcccatgacctatactcaggcttcaggttatagtcaa
ggatatgctggctcaacttcctactttgggggcatggac
tgtggatcatatttgacccctatgcatcaccagcttccc
ggaccaggggccacactcagtcccatgggtaccaatgca
gtcaccagccatctcaatcagtccccagcttctctttcc
acccagggatatggagcttcaagcttgggttttaactca
accactgattgcttggattataaggaccaaactgcctcc
tggaagcttaacttcaatgctgactgcttggattataaa
gatcagacatcctcgtggaaattccaggttttgtga
other info1 :
Vector: Please Inquire
ncbi gi num :
21618611
ncbi acc num :
BC032579
ncbi mol weight :
32,406 Da
ncbi pathways :
TP53 Network Pathway (198896)
ncbi summary :
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
uniprot summary :
OTX2: Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'. Expressed in brain. Belongs to the paired homeobox family. Bicoid subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 14q22.3. Cellular Component: growth cone; nucleus; protein complex. Molecular Function: eukaryotic initiation factor 4E binding; protein binding. Biological Process: axon guidance; forebrain development; midbrain development; positive regulation of embryonic development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein complex assembly; regulation of fibroblast growth factor receptor signaling pathway; regulation of smoothened signaling pathway. Disease: Microphthalmia, Syndromic 5; Pituitary Hormone Deficiency, Combined, 6
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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