product summary
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company name :
MyBioSource
product type :
cDNA
product name :
TFAM cDNA Clone
catalog :
MBS1276975
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1276975
products type :
cDNA Clone
products full name :
TFAM cDNA Clone
products short name :
TFAM
other names :
Homo sapiens transcription factor A, mitochondrial, mRNA; Transcription factor A, mitochondrial; transcription factor A, mitochondrial; transcription factor A, mitochondrial; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2
products gene name :
TFAM
other gene names :
TFAM; TFAM; TCF6; MTTF1; MTTFA; TCF6L1; TCF6L2; TCF6L3; TCF6; TCF6L2; mtTFA; MtTF1; TCF-6
uniprot entry name :
TFAM_HUMAN
sequence length :
1772
sequence :
atggcgtttctccgaagcatgtggggcgtgctgagtgcc
ctgggaaggtctggagcagagctgtgcaccggctgtgga
agtcgactgcgctcccccttcagttttgtgtatttaccg
aggtggttttcatctgtcttggcaagttgtccaaagaaa
cctgtaagttcttaccttcgattttctaaagaacaacta
cccatatttaaagctcagaacccagatgcaaaaactaca
gaactaattagaagaattgcccagcgttggagggaactt
cctgattcaaagaaaaaaatatatcaagatgcttatagg
gcggagtggcaggtatataaagaagagataagcagattt
aaagaacagctaactccaagtcagattatgtctttggaa
aaagaaatcatggacaaacatttaaaaaggaaagctatg
acaaaaaaaaaagagttaacactgcttggaaaaccaaaa
agacctcgttcagcttataacgtttatgtagctgaaaga
ttccaagaagctaagggtgattcaccgcaggaaaagctg
aagactgtaaaggaaaactggaaaaatctgtctgactct
gaaaaggaattatatattcagcatgctaaagaggacgaa
actcgttatcataatgaaatgaagtcttgggaagaacaa
atgattgaagttggacgaaaggatcttctacgtcgcaca
ataaagaaacaacgaaaatatggtgctgaggagtgttaa
other info1 :
Vector: Please Inquire
ncbi gi num :
116496710
ncbi acc num :
BC126366
ncbi mol weight :
25,466 Da
ncbi pathways :
Energy Metabolism Pathway (198907); Gene Expression Pathway (105937); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Mitochondrial Gene Expression Pathway (198757); Mitochondrial Transcription Initiation Pathway (106569); RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway (160948); Transcription From Mitochondrial Promoters Pathway (106568)
ncbi summary :
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
uniprot summary :
TFAM: regulates mitochondrial transcription. Induced in humans by caloric restriction. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Activates transcription by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Involved in cisplatin resistance. Interacts with TFB1M and TFB2M. Protein type: DNA-binding; Transcription regulation. Chromosomal Location of Human Ortholog: 10q21. Cellular Component: cytosol; mitochondrial matrix; mitochondrion; nucleus. Molecular Function: chromatin binding; DNA bending activity; protein binding; transcription factor activity. Biological Process: DNA-dependent DNA replication; mitochondrion organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase I promoter; transcription from mitochondrial promoter; transcription initiation from mitochondrial promoter
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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