product summary
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company name :
MyBioSource
product type :
cDNA
product name :
RHOQ cDNA Clone
catalog :
MBS1276587
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1276587
products type :
cDNA Clone
products full name :
RHOQ cDNA Clone
products short name :
RHOQ
other names :
Homo sapiens ras homolog gene family, member Q, mRNA; Rho-related GTP-binding protein RhoQ; rho-related GTP-binding protein RhoQ; ras homolog family member Q; Ras-like protein TC10; Ras-like protein family member 7A
products gene name :
RHOQ
other gene names :
RHOQ; RHOQ; ARHQ; TC10; TC10A; RASL7A; HEL-S-42; ARHQ; RASL7A; TC10
uniprot entry name :
RHOQ_HUMAN
sequence length :
1947
sequence :
ATGGCTCACGGGCCCGGCGCGCTGATGCTCAAGTGCGTG
GTGGTCGGCGACGGGGCGGTGGGCAAGACGTGCCTACTC
ATGAGCTATGCCAACGACGCCTTCCCGGAGGAGTACGTG
CCCACCGTCTTCGACCACTACGCAGTCAGCGTCACCGTG
GGGGGCAAGCAGTACCTCCTAGGACTCTATGACACGGCC
GGACAGGAAGACTATGACCGTCTGAGGCCTTTATCTTAC
CCAATGACCGATGTCTTCCTTATATGCTTCTCGGTGGTA
AATCCAGCCTCATTTCAAAATGTGAAAGAGGAGTGGGTA
CCGGAACTTAAGGAATACGCACCAAATGTACCCTTTTTA
TTAATAGGAACTCAGATTGATCTCCGAGATGACCCCAAA
ACTTTAGCAAGACTGAATGATATGAAAGAAAAACCTATA
TGTGTGGAACAAGGACAGAAACTAGCAAAAGAGATAGGA
GCATGCTGCTATGTGGAATGTTCAGCTTTAACCCAGAAG
GGATTGAAGACTGTTTTTGATGAGGCTATCATAGCCATT
TTAACTCCAAAGAAACACACTGTAAAAAAAAGAATAGGA
TCAAGATGTATAAACTGTTGTTTAATTACGTGA
other info1 :
Vector: Please Inquire
ncbi gi num :
33440525
ncbi acc num :
BC056154
ncbi mol weight :
22,659 Da
ncbi pathways :
Insulin Pathway (138026); Insulin Signaling Pathway (198845); Insulin Signaling Pathway (83090); Insulin Signaling Pathway (501); Insulin-mediated Glucose Transport Pathway (137981); Membrane Trafficking Pathway (106160); Rho GTPase Cycle Pathway (106503); Signal Transduction Pathway (477114); Signaling By Rho GTPases Pathway (106502); Translocation Of GLUT4 To The Plasma Membrane Pathway (685554)
ncbi summary :
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]
uniprot summary :
RHOQ: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. Belongs to the small GTPase superfamily. Rho family. Protein type: G protein, monomeric; G protein; Motility/polarity/chemotaxis; G protein, monomeric, Rho. Chromosomal Location of Human Ortholog: 2p21. Cellular Component: actin filament; cytosol; plasma membrane. Molecular Function: GBD domain binding; GTPase activity; profilin binding. Biological Process: cellular response to insulin stimulus; cortical actin cytoskeleton organization and biogenesis; GTP metabolic process; insulin receptor signaling pathway; positive regulation of filopodium formation; positive regulation of glucose import; positive regulation of transcription from RNA polymerase II promoter; regulation of actin cytoskeleton organization and biogenesis; regulation of small GTPase mediated signal transduction
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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