product summary
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company name :
MyBioSource
product type :
cDNA
product name :
ARHGEF9 cDNA Clone
catalog :
MBS1276404
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1276404
products type :
cDNA Clone
products full name :
ARHGEF9 cDNA Clone
products short name :
ARHGEF9
other names :
Homo sapiens Cdc42 guanine nucleotide exchange factor (GEF) 9, mRNA; Rho guanine nucleotide exchange factor 9; rho guanine nucleotide exchange factor 9; Cdc42 guanine nucleotide exchange factor 9; Collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9
products gene name :
ARHGEF9
other gene names :
ARHGEF9; ARHGEF9; PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN; ARHDH9; KIAA0424
uniprot entry name :
ARHG9_HUMAN
sequence length :
2016
sequence :
atgacgttgctgatcactggagattccatcgttagtgct
gaggcagtatgggatcacgtcaccatggccaaccgggag
ttggcatttaaagctggcgacgtcatcaaagtcttggat
gcttccaacaaggattggtggtggggccagatcgacgat
gaggagggatggtttcctgccagctttgtgaggctctgg
gtgaaccaggaggatgaggtggaggaggggcccagcgat
gtgcagaacggacacctggaccccaattcagactgcctc
tgtctggggcggccactacagaaccgggaccagatgcgg
gccaatgtcatcaatgagataatgagcactgagcgtcac
tacatcaagcacctcaaggatatttgtgagggctatctg
aagcagtgccggaagagaagggacatgttcagtgacgag
caactgaaggtaatctttgggaacattgaagatatctac
agatttcagatgggctttgtgagagacctggagaaacag
tataacaatgatgacccccacctcagcgagataggaccc
tgcttcctagagcaccaagatggattctggatatactct
gagtattgtaacaaccacctggatgcttgcatggagctc
tccaaactgatgaaggacagccgctaccagcacttcttt
gaggcctgtcgcctcttgcagcagatgattgacattgct
atcgatggtttccttttgactccagtgcagaagatctgc
aagtatcccttacagttggctgagctcctaaagtatact
gcccaagaccacagtgactacaggtatgtggcagctgct
ttggctgtcatgagaaatgtgactcagcagatcaacgaa
cgcaagcgacgtttagagaatattgacaagattgctcag
tggcaggcttctgtcctagactgggagggcgaggacatc
ctagacaggagctcggagctgatctacactggggagatg
gcctggatctaccagccctacggccgcaaccagcagcgg
gtcttcttcctgtttgaccaccagatggtcctctgcaag
aaggacctaatccggagagacatcctgtactacaaaggc
cgcattgacatggataaatatgaggtagttgacattgag
gatggcagagatgatgacttcaatgtcagcatgaagaat
gcctttaagcttcacaacaaggagactgaggagatacat
ctgttctttgccaagaagctggaggaaaaaatacgctgg
ctcagggctttcagagaagagaggaaaatggtacaggaa
gatgaaaaaattggctttgaaatttctgaaaaccagaag
aggcaggctgcaatgactgtgagaaaagtccctaagcaa
aaaggtgtcaactctgcccgctcagttcctccttcctac
ccaccaccgcaggacccgttaaaccacggccagtacctg
gtccccgacggcatcgctcagtcgcaggtctttgagttc
accgaacccaagcgcagccagtcaccattctggcaaaac
ttcagcaggttaacccccttcaaaaaatga
other info1 :
Vector: Please Inquire
ncbi gi num :
111599692
ncbi acc num :
BC117406
ncbi mol weight :
49,458 Da
ncbi pathways :
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); G Alpha (12/13) Signalling Events Pathway (106041); GABA A Receptor Activation Pathway (187179); GABA Receptor Activation Pathway (187178); GPCR Downstream Signaling Pathway (119548); Ion Channel Transport Pathway (187193); Ligand-gated Ion Channel Transport Pathway (187195); NRAGE Signals Death Through JNK Pathway (106444); Neuronal System Pathway (106513); Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway (106534)
ncbi summary :
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
uniprot summary :
ARHGEF9: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters. Defects in ARHGEF9 are the cause of pileptic encephalopathy, early infantile, type 8 (EIEE8). A disorder characterized by hyperekplexia and early infantile epileptic encephalopathy. Neurologic features include exaggerated startle response, seizures, impaired psychomotor development, and mental retardation. Seizures can be provoked by tactile stimulation or extreme emotion. 2 isoforms of the human protein are produced by alternative splicing. Protein type: GAPs; GAPs, Rac/Rho. Chromosomal Location of Human Ortholog: Xq11.1. Cellular Component: cytoplasm; cytosol. Molecular Function: guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity. Biological Process: positive regulation of apoptosis; regulation of small GTPase mediated signal transduction. Disease: Epileptic Encephalopathy, Early Infantile, 8
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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