product summary
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company name :
MyBioSource
product type :
antibody
product name :
GLO1 Polyclonal Antibody
catalog :
MBS127611
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using GLO1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
image 2 :
Immunohistochemistry of paraffin-embedded mouse kidney using GLO1 antibody at dilution of 1:200 (40x lens).
product information
catalog number :
MBS127611
products type :
Antibody
products full name :
GLO1 Polyclonal Antibody
products short name :
[GLO1]
products name syn :
[GLYI; GLOD1; HEL-S-74]
other names :
[Lactoylglutathione lyase; Lactoylglutathione lyase; lactoylglutathione lyase; glx I; aldoketomutase; methylglyoxalase; ketone-aldehyde mutase; lactoyl glutathione lyase; glyoxalase domain containing 1; epididymis secretory protein Li 74; S-D-lactoylglutathione methylglyoxal lyase; glyoxalase I; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase]
products gene name :
[GLO1]
other gene names :
[GLO1; GLO1; GLYI; GLOD1; HEL-S-74; Glx I]
uniprot entry name :
LGUL_HUMAN
clonality :
polyclonal
isotype :
IgG
host :
unknown
reactivity :
Human, Mouse, Rat
sequence length :
184
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze/thaw cycles
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC/IF: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit. Immunogen: Recombinant protein of human GLO1
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
ncbi gi num :
134039205
ncbi acc num :
Q04760.4
uniprot acc num :
Q04760
ncbi mol weight :
Calculated: 19kDa/20kDa. Observed: 21kDa
ncbi pathways :
Pyruvate Metabolism Pathway (82998); Pyruvate Metabolism Pathway (373); Methylglyoxal Degradation I Pathway (142313)
ncbi summary :
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
uniprot summary :
GLO1: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B. Belongs to the glyoxalase I family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Carbohydrate Metabolism - pyruvate; EC 4.4.1.5; Lyase. Chromosomal Location of Human Ortholog: 6p21.3-p21.1. Cellular Component: cytoplasm. Molecular Function: zinc ion binding; lactoylglutathione lyase activity. Biological Process: regulation of transcription from RNA polymerase II promoter; glutathione metabolic process; carbohydrate metabolic process; osteoclast differentiation; methylglyoxal metabolic process; negative regulation of apoptosis. Disease: Autism
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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