product summary
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company name :
MyBioSource
product type :
cDNA
product name :
SNX1 cDNA Clone
catalog :
MBS1275849
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1275849
products type :
cDNA Clone
products full name :
SNX1 cDNA Clone
products short name :
SNX1
other names :
Homo sapiens sorting nexin 1, mRNA; Sorting nexin-1; sorting nexin-1; sorting nexin 1
products gene name :
SNX1
other gene names :
SNX1; SNX1; VPS5; HsT17379
uniprot entry name :
SNX1_HUMAN
sequence length :
1982
sequence :
atggcgtcgggtggtggtggctgtagcgcttcggagaga
ctgcctccgcccttccccggcctggagccggagtccgag
ggggcggccgggggatcagaacccgaggctggggacagc
gacaccgagggggaggacattttcaccggcgccgcggtg
gtcagtaaacatcagtctccaaagataactacatccctt
cttcccatcaacaatggctccaaagaaaatgggatccat
gaagaacaagaccaagagccacaggatctctttgcagat
gccacagtggagctatccttggacagcacacaaaataat
cagaagaaggtgctagccaaaacactcatttctcttcct
cctcaggaagccacaaattcttcgaagccccagccaacc
tatgaggagctagaggaagaagaacaggaggatcaattt
gatttgacagtcggtataactgatcctgagaagataggg
gatggtatgaatgcatatgtagcctacaaagttacaaca
cagacaagcttaccattgttcagaagcaaacagtttgca
gtaaaaagaagatttagtgactttctgggtctttatgag
aagctttccgagaagcactctcagaatggcttcattgtc
cctccacccccggagaagagcctcatagggatgacaaaa
gtgaaagttgggaaggaagattcttcttctgcagaattt
cttgaaaaacggagggccgctttagaaaggtaccttcag
aggattgtaaatcatcctaccatgttacaggaccctgac
gtcagagagttcttggaaaaagaagagctgccacgtgcc
gtgggtacccagacattgagtggtgctggtctcctcaag
atgttcaacaaagccacagatgccgtcagcaaaatgacc
atcaagatgaatgaatcagacatttggtttgaggagaag
ctccaggaggtagagtgtgaggagcagcgcttacggaaa
ctgcatgctgttgtagaaactctagtcaaccataggaaa
gagctagcgctgaacacagcccagtttgcaaagagtcta
gccatgcttgggagctctgaggacaacacggcattgtca
cgggcactctcccagctggctgaggtggaagaaaaaatt
gagcagctccaccaggaacaggccaacaatgacttcttc
ctccttgctgagctcctgagtgactacattcgcctcctg
gccatagtccgcgctgccttcgaccagcgcatgaagaca
tggcagcgctggcaggatgcccaagccacactgcagaag
aagcgggaggccgaggctcggctgctgtgggccaacaag
cctgataagctgcagcaggccaaggacgagatcctcgag
tgggagtctcgggtgactcaatatgaaagggacttcgag
aggatttcaacagtggtccgaaaagaagtgatacggttt
gagaaagagaaatccaaggacttcaagaaccacgtgatc
aagtaccttgagacactcctttactcacagcagcagctg
gcaaagtactgggaagccttccttcctgaggcaaaggcc
atctcctaa
other info1 :
Vector: Please Inquire
ncbi gi num :
38197125
ncbi acc num :
BC000357
ncbi mol weight :
63,082 Da
ncbi pathways :
TGF-beta Receptor Signaling Pathway (198774)
ncbi summary :
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
SNX1: May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3- phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 15q22.31. Cellular Component: cell-cell adherens junction; cytoplasm; early endosome membrane; endosome membrane; extrinsic to membrane; intracellular membrane-bound organelle; membrane; protein complex; retromer complex; vesicle. Molecular Function: epidermal growth factor receptor binding; identical protein binding; insulin receptor binding; phosphoinositide binding; protein binding; protein heterodimerization activity; protein homodimerization activity. Biological Process: intracellular protein transport; receptor internalization; retrograde transport, endosome to Golgi; vesicle organization and biogenesis
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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