product summary
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company name :
MyBioSource
product type :
cDNA
product name :
CCT2 cDNA Clone
catalog :
MBS1274673
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1274673
products type :
cDNA Clone
products full name :
CCT2 cDNA Clone
products short name :
CCT2
other names :
Homo sapiens chaperonin containing TCP1, subunit 2 (beta), mRNA; T-complex protein 1 subunit beta; T-complex protein 1 subunit beta; chaperonin containing TCP1 subunit 2; CCT-beta
products gene name :
CCT2
other gene names :
CCT2; CCT2; CCTB; 99D8.1; PRO1633; CCT-beta; HEL-S-100n; TCP-1-beta; 99D8.1; CCTB; TCP-1-beta
uniprot entry name :
TCPB_HUMAN
sequence length :
1703
sequence :
atggcgtccctttcccttgcacctgttaacatctttaag
gcaggagctgatgaagagagagcagagacagctcgtctg
acttcttttattggtgccatcgccattggagacttggta
aagagcaccttgggacccaaaggcatggacaaaattctt
ctaagcagtggacgagatgcctctcttatggtaaccaat
gatggtgccactattctaaaaaacattggtgttgacaat
ccagcagctaaagttttagttgatatgtcaagggttcaa
gatgatgaagttggtgatggcactacctctgttaccgtt
ttagcagcagaattattaagggaagcagaatctttaatt
gcaaaaaagattcatccacagaccatcatagcgggttgg
agagaagccacgaaggctgcaagagaggcgctgttgagt
tctgcagttgatcatggttccgatgaagttaaattccgt
caagatttaatgaatattgcgggcacaacattatcctca
aaacttcttactcatcacaaagaccactttacaaagtta
gctgtagaagcagttctcagactgaaaggctctggcaac
ctggaggcaattcatattatcaagaagctaggaggaagt
ttggcagattcctatttagatgaaggcttcctgttggat
aaaaaaattggagtaaatcaaccaaaacgaattgaaaat
gctaaaattcttattgcaaatactggtatggatacagac
aaaataaagatatttggttcccgggtaagagttgactct
acggcaaaggttgcagaaatagaacatgcggaaaaggaa
aaaatgaaggagaaagttgaacgtattcttaagcatgga
ataaattgctttattaacaggcaattaatttataattat
cctgaacagctctttggtgctgctggtgtcatggctatt
gagcatgcagattttgcaggtgtggaacgcctagctctt
gtcacaggtggtgaaattgcctctacctttgatcaccca
gaactggtgaagcttggaagttgcaaacttatcgaggaa
gtcatgattggagaagacaaactcattcacttttctggg
gttgcccttggtgaggcttgtaccattgttttgcgtggt
gccactcaacaaattttagatgaagcagaaagatcattg
catgatgctctttgtgttcttgcgcaaactgtaaaggac
tctagaacagtttatggaggaggctgttctgagatgttg
atggctcatgctgtgacacagcttgccaatagaacacca
ggcaaagaagctgttgcaatggagtcttatgctaaagca
ctgagaatgttgccaaccatcatagctgacaatgcaggc
tatgacagtgcagacctggtggcacagctcagggctgct
cacagtgaaggcaataccactgctggattggatatgagg
gaaggcaccattggagatatggctatcctgggtataaca
gaaagttttcaagtgaagcgacaggttcttctgagtgca
gctgaagcagcagaggtgattctgcgtgtggacaacatc
atcaaagcggcacccaggaaacgtgtccctgatcaccac
ccctgttaa
other info1 :
Vector: Please Inquire
ncbi gi num :
109730510
ncbi acc num :
BC113516
ncbi mol weight :
52,718 Da
ncbi pathways :
Association Of TriC/CCT With Target Proteins During Biosynthesis Pathway (106247); Chaperonin-mediated Protein Folding Pathway (106242); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (106243); Folding Of Actin By CCT/TriC Pathway (106246); Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway (106245); Metabolism Of Proteins Pathway (106230); Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway (106244); Protein Folding Pathway (106241)
ncbi summary :
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
uniprot summary :
CCT2: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8. Belongs to the TCP-1 chaperonin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Chaperone. Chromosomal Location of Human Ortholog: 12q15. Cellular Component: chaperonin-containing T-complex; cytoplasm; cytosol; extracellular matrix; microtubule. Molecular Function: protein binding; ubiquitin protein ligase binding. Biological Process: chaperone cofactor-independent protein folding; chaperone-mediated protein complex assembly; positive regulation of telomerase activity; positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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