SFPQ Polyclonal Antibody | MyBioSource MBS127424 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SFPQ Polyclonal Antibody

catalog :

MBS127424

quantity :

0.05 mL

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of various cell lines, using SFPQ antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

image 2 :

Immunohistochemistry of paraffin-embedded rat brain using SFPQ antibody at dilution of 1:100 (40x lens).

image 3 :

Immunohistochemistry of paraffin-embedded human lung cancer using SFPQ antibody at dilution of 1:100 (40x lens).

product information

catalog number :

MBS127424

products type :

Antibody

products full name :

SFPQ Polyclonal Antibody

products short name :

[SFPQ]

products name syn :

[SFPQ; POMP100; PPP1R140; PSF; splicing factorproline and glutamine rich]

other names :

[Splicing factor, proline- and glutamine-rich; Splicing factor, proline- and glutamine-rich; splicing factor, proline- and glutamine-rich; hPOMp100; 100 kDa DNA-pairing protein; PTB-associated splicing factor; PTB-associated-splicing factor; DNA-binding p52/p100 complex, 100 kDa subunit; protein phosphatase 1, regulatory subunit 140; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; polypyrimidine tract-binding protein-associated-splicing factor; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated); splicing factor proline/glutamine-rich; 100 kDa DNA-pairing protein; hPOMp100; DNA-binding p52/p100 complex, 100 kDa subunit; Polypyrimidine tract-binding protein-associated-splicing factor; PSF; PTB-associated-splicing factor]

products gene name :

[SFPQ]

other gene names :

[SFPQ; SFPQ; PSF; POMP100; PPP1R140; PSF; hPOMp100; PSF; PTB-associated-splicing factor]

uniprot entry name :

SFPQ_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

707

purity :

Affinity Purification

form :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

storage stability :

Store at -20 degree C. Avoid freeze / thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

app notes :

WB: 1:500 - 1:1000. IHC 1:50 - 1:100. IF 1:50 - 1:100

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

Immunohistochemistry of paraffin-embedded human esophageal cancer using SFPQ antibody at dilution of 1:100 (40x lens).

image5 heading :

Immunohistochemistry (IHC)

image5 description :

Immunohistochemistry of paraffin-embedded human stomach using SFPQ antibody at dilution of 1:100 (40x lens).

other info2 :

Immunogen: Recombinant fusion protein containing a sequencecorresponding to amino acids 578-707 of human SFPQ(NP_005057.1)

products categories :

Polyclonal

ncbi gi num :

1709851

ncbi acc num :

P23246.2

uniprot acc num :

P23246

ncbi mol weight :

Calculated MW: 72kDa/76kDa. Observed MW: 115kDa

ncbi pathways :

MRNA Processing Pathway (198843)

uniprot summary :

PSF: a proline-and glutamine-rich splicing factor. Essential pre-mRNA splicing factor required early in spliceosome formation. Seems to also bind DNA. The active complex is a heterotetramer of two 52 kDa and two 100 kDa subunits. Reported to be a PKC-alpha-binding protein in the cell nucleus. Two alternatively spliced isoforms have been described. Protein type: RNA splicing; RNA-binding; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 1p34.3. Cellular Component: nucleoplasm; nuclear matrix; cytoplasm; nucleus; paraspeckles; chromatin. Molecular Function: protein binding; histone deacetylase binding; nucleotide binding. Biological Process: alternative nuclear mRNA splicing, via spliceosome; transcription, DNA-dependent; RNA splicing; rhythmic process; negative regulation of circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; DNA repair; mRNA processing; negative regulation of transcription, DNA-dependent; regulation of circadian rhythm; DNA recombination

size1 :

0.05 mL

price1 :

200 USD

size2 :

0.1 mL

price2 :

275

size3 :

0.2 mL

price3 :

430

more info or order :

MyBioSource product webpage