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company name :
MyBioSource
product type :
cDNA
product name :
HMGB1 cDNA Clone
catalog :
MBS1273983
quantity :
0.01 mg Plasmid + 0.
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1273983
products type :
cDNA Clone
products full name :
HMGB1 cDNA Clone
products short name :
HMGB1
other names :
Homo sapiens high-mobility group box 1, mRNA; High mobility group protein B1; high mobility group protein B1; HMG-1; Amphoterin; high-mobility group box 1; high mobility group protein 1; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1; high mobility group box 1; High mobility group protein 1
products gene name :
HMGB1
other gene names :
HMGB1; HMGB1; HMG1; HMG3; SBP-1; HMG1; HMG-1
uniprot entry name :
HMGB1_HUMAN
sequence length :
1207
sequence :
ATGGGCAAAGGAGATCCTAAGAAGCCGAGAGGCAAAATG
TCATCATATGCATTTTTTGTGCAAACTTGTCGGGAGGAG
CATAAGAAGAAGCACCCAGATGCTTCAGTCAACTTCTCA
GAGTTTTCTAAGAAGTGCTCAGAGAGGTGGAAGACCATG
TCTGCTAAAGAGAAAGGAAAATTTGAAGATATGGCAAAG
GCGGACAAGGCCCGTTATGAAAGAGAAATGAAAACCTAT
ATCCCTCCCAAAGGGGAGACAAAAAAGAAGTTCAAGGAT
CCCAATGCACCCAAGAGGCCTCCTTCGGCCTTCTTCCTC
TTCTGCTCTGAGTATCGCCCAAAAATCAAAGGAGAACAT
CCTGGCCTGTCCATTGGTGATGTTGCGAAGAAACTGGGA
GAGATGTGGAATAACACTGCTGCAGATGACAAGCAGCCT
TATGAAAAGAAGGCTGCGAAGCTGAAGGAAAAATACGAA
AAGGATATTGCTGCATATCGAGCTAAAGGAAAGCCTGAT
GCAGCAAAAAAGGGAGTTGTCAAGGCTGAAAAAAGCAAG
AAAAAGAAGGAAGAGGAGGAAGATGAGGAAGATGAAGAG
GATGAGGAGGAGGAGGAAGATGAAGAAGATGAAGATGAA
GAAGAAGATGATGATGATGAATAA
other info1 :
Vector: Please Inquire. Accession Number: BC0033781. cDNA Size: 648. Gene ID: 3146
products description :
Homo sapiens high-mobility group box 1, mRNA (cDNA clone MGC:5223 IMAGE:2901382), complete cds.
ncbi gi num :
13097233
ncbi acc num :
BC003378
uniprot acc num :
P09429
ncbi mol weight :
24,894 Da
ncbi pathways :
Activated TLR4 Signalling Pathway (106400); Activation Of DNA Fragmentation Factor Pathway (105683); Advanced Glycosylation Endproduct Receptor Signaling Pathway (187092); Apoptosis Pathway (105648); Apoptosis Induced DNA Fragmentation Pathway (105682); Apoptotic Execution Phase Pathway (105677); Base Excision Repair Pathway (83043); Base Excision Repair Pathway (451); Cytosolic Sensors Of Pathogen-associated DNA Pathway (576255); DAI Mediated Induction Of Type I IFNs Pathway (576256)
uniprot summary :
HMGB1: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells. Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. Belongs to the HMGB family. Protein type: Nuclear receptor co-regulator; DNA repair, damage. Chromosomal Location of Human Ortholog: 13q12. Cellular Component: nucleoplasm; extracellular space; cell surface; transcriptional repressor complex; extracellular region; condensed chromosome; nucleus. Molecular Function: protein binding; RAGE receptor binding; double-stranded DNA binding; damaged DNA binding; cytokine activity; chromatin binding; transcription factor binding; transcription factor activity; DNA bending activity; single-stranded DNA binding; chemoattractant activity. Biological Process: negative regulation of transcriptional preinitiation complex assembly; V(D)J recombination; DNA topological change; positive regulation of apoptosis; apoptosis; positive regulation of caspase activity; base-excision repair, DNA ligation; negative regulation of transcription from RNA polymerase II promoter; DNA recombination; chromatin remodeling; regulation of transcription from RNA polymerase II promoter; myeloid dendritic cell activation; inflammatory response to antigenic stimulus; positive chemotaxis; DNA ligation during DNA repair; innate immune response; dendritic cell chemotaxis; positive regulation of transcription from RNA polymerase II promoter; DNA fragmentation during apoptosis; neurite development; positive regulation of DNA binding; cell structure disassembly during apoptosis
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
175 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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