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company name :
MyBioSource
product type :
cDNA
product name :
UNC45B cDNA Clone
catalog :
MBS1273658
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1273658
products type :
cDNA Clone
products full name :
UNC45B cDNA Clone
products short name :
UNC45B
other names :
Homo sapiens unc-45 homolog B (C. elegans), mRNA; Protein unc-45 homolog B; protein unc-45 homolog B; unc-45 myosin chaperone B; SMUNC45
products gene name :
UNC45B
other gene names :
UNC45B; UNC45B; CMYA4; UNC45; CTRCT43; SMUNC45; UNC-45B; CMYA4; UNC45; Unc-45B
uniprot entry name :
UN45B_HUMAN
sequence length :
2790
sequence :
ATGGCAGAGGTGGAAGCGGTACAGCTGAAGGAGGAAGGA
AACCGGCATTTCCAGCTCCAGGACTACAAGGCCGCCACA
AATAGCTACAGCCAGGCCCTGAAGCTGACCAAGGACAAG
GCCCTGCTGGCCACGCTTTATCGGAACCGGGCAGCCTGT
GGCCTGAAAACGGAGAGCTACATCCAGGCAGCTTCAGAT
GCCTCCAGAGCCATCGACATCAACTCCTCGGACATCAAG
GCTCTGTATCGGCGATGCCAGGCACTGGAGCACCTGGGG
AAGCTGGACCAGGCCTTCAAAGACGTGCAGCGTTGTGCC
ACCCTCGAGCCACGGAACCAGAACTTCCAGGAGATGCTG
AGGAGACTCAACACCAGCATTCAGGAGAAGCTCCGAGTG
CAGTTCTCCACAGACTCGAGGGTACAGAAGATGTTTGAG
ATCCTCTTGGATGAAAACAGTGAGGCTGATAAGCGGGAA
AAGGCTGCCAACAATCTCATTGTCCTAGGCCGTGAGGAA
GCAGGGGCTGAGAAGATCTTCCAGAACAATGGAGTAGCC
TTGCTACTGCAGCTTCTGGACACTAAGAAGCCTGAGCTG
GTGCTGGCTGCAGTGCGGACCCTGTCGGGCATGTGCAGC
GGCCACCAAGCCAGAGCCACAGTGATTCTGCATGCAGTG
CGGATAGACCGAATCTGTAGCCTCATGGCCGTGGAGAAT
GAGGAGATGTCTCTGGCTGTCTGCAACCTGCTCCAAGCC
ATCATTGACTCCTTGTCTGGGGAGGACAAGCGGGAGCAT
CGAGGGAAGGAGGAGGCCCTGGTTCTAGACACCAAGAAG
GACCTGAAGCAGATCACCAGCCACCTGCTGGACATGCTA
GTCAGCAAGAAGGTGTCTGGCCAGGGCAGGGATCAGGCG
CTGAACCTGCTCAATAAGAATGTTCCCAGGAAGGACCTT
GCCATTCATGACAACTCACGTACCATCTATGTGGTGGAT
AATGGTCTGAGGAAGATCCTGAAGGTTGTGGGGCAGGTT
CCAGATCTGCCATCCTGCCTGCCCCTGACTGACAACACC
CGCATGCTGGCCTCTATCCTCATCAACAAGCTCTATGAT
GACCTGCGCTGTGACCCGGAGCGCGATCACTTCCGCAAG
ATCTGTGAGGAATATATCACGGGCAAGTTTGACCCCCAG
GACATGGACAAGAACTTGAATGCCATCCAGACAGTGTCA
GGGATCCTGCAGGGCCCCTTTGACCTGGGCAACCAGCTG
CTGGGACTGAAAGGTGTGATGGAGATGATGGTGGCACTA
TGTGGCTCAGAGCGCGAGACGGACCAGCTGGTGGCCGTG
GAGGCCCTCATCCATGCCTCCACGAAGCTCAGCCGCGCC
ACCTTCATCATCACCAATGGAGTGTCACTGCTCAAACAG
ATCTACAAGACCACCAAAAATGAGAAGATCAAGATCCGC
ACACTGGTGGGACTCTGTAAGCTCGGCTCTGCAGGTGGC
ACAGACTACGGTCTCAGGCAGTTTGCGGAAGGGTCGACA
GAAAAACTGGCCAAACAGTGTCGCAAGTGGCTGTGCAAT
ATGTCCATAGACACTCGGACCCGACGCTGGGCAGTGGAG
GGCCTGGCCTACCTCACGCTGGACGCTGATGTGAAGGAC
GACTTTGTCCAGGACGTCCCTGCCCTGCAGGCCATGTTT
GAGCTGGCCAAGACCAGTGACAAGACCATCCTGTACTCG
GTGGCCACCACCCTGGTGAACTGCACCAACAGCTACGAT
GTCAAGGAGGTCATCCCAGAGCTTGTCCAGCTCGCCAAG
TTCTCCAAGCAGCATGTGCCCGAGGAACACCCCAAGGAC
AAGAAGGACTTTATAGACATGCGGGTGAAGCGGCTTCTG
AAGGCGGGTGTCATCTCTGCCCTGGCTTGCATGGTGAAA
GCAGATAGTGCCATCCTCACTGACCAGACCAAGGAGCTG
CTGGCCAGGGTATTCCTGGCACTGTGTGACAACCCAAAG
GACCGAGGCACCATTGTGGCTCAAGGTGGTGGCAAGGCC
CTGATTCCCCTGGCTTTGGAGGGCACAGATGTGGGCAAG
GTGAAGGCAGCCCACGCTCTAGCAAAGATCGCTGCTGTC
TCCAATCCGGACATTGCTTTTCCTGGGGAGCGGGTGTAT
GAGGTGGTGCGGCCCCTTGTAAGACTCTTGGACACACAG
AGGGATGGGCTTCAGAACTATGAGGCTCTCCTAGGCCTC
ACCAACCTGTCTGGGCGGAGTGACAAACTCCGGCAGAAG
ATCTTTAAGGAGAGGGCCTTGCCAGACATCGAGAACTAC
ATGTTTGAGAATCATGATCAGCTGCGGCAGGCGGCCACC
GAGTGCATGTGCAACATGGTGCTCCACAAGGAGGTACAG
GAAAGGTTCTTGGCTGACGGGAATGACCGGCTGAAGCTG
GTGGTGCTGCTCTGCGGGGAGGATGATGATAAGGTGCAG
AATGCGGCTGCAGGGGCTCTGGCCATGCTGACAGCAGCA
CACAAGAAACTGTGCCTCAAGATGACTCAAGTGACAACC
CAGTGGTTGGAGATCCTCCAGCGGCTTTGCCTGCACGAC
CAGCTGTCTGTCCAACACCGGGGCCTGGTCATTGCCTAC
AACCTACTGGCAGCCGATGCTGAGCTGGCCAAGAAGCTG
GTGGAGAGTGAGCTGCTGGAGATCCTGACTGTGGTGGGC
AAACAGGAGCCAGATGAGAAGAAGGCAGAAGTGGTTCAG
ACAGCCCGAGAATGTCTCATCAAGTGCATGGATTATGGT
TTCATTAAACCAGTGTCTTAG
other info1 :
Vector: Please Inquire
ncbi gi num :
72533320
ncbi acc num :
BC101063
ncbi mol weight :
103,605 Da
ncbi summary :
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
uniprot summary :
UNC45B: Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 17q12. Cellular Component: cytoplasm. Molecular Function: protein binding. Biological Process: lens development in camera-type eye. Disease: Cataract 43
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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