catalog number :
MBS127291
products full name :
ACADM Polyclonal Antibody
products short name :
ACADM
products name syn :
MCAD; ACAD1; MCADH
other names :
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; acyl-CoA dehydrogenase, C-4 to C-12 straight chain
products gene name :
ACADM
other gene names :
ACADM; ACADM; MCAD; ACAD1; MCADH; MCAD
uniprot entry name :
ACADM_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
other info1 :
Species: Human. Route: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human ACADM. Calculated Molecular Weight: 46kDa
products categories :
Polyclonal
products description :
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ncbi pathways :
Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway 106127!!Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway 106128!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Fatty Acid Beta Oxidation Pathway 198865!!Fatty Acid Degradation Pathway 82935!!Fatty Acid Degradation Pathway 296!!Fatty Acid Metabolism Pathway 868084!!Fatty Acid Metabolism Pathway 878045
ncbi summary :
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]