catalog number :
MBS127264
products full name :
SCTR Polyclonal Antibody
products short name :
[SCTR]
other names :
[Secretin receptor; Secretin receptor; secretin receptor; pancreatic secretin receptor; secretin receptor]
products gene name :
[SCTR]
other gene names :
[SCTR; SCTR; SR; SCT-R]
uniprot entry name :
SCTR_HUMAN
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze/thaw cycles
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Immunogen: Recombinant protein of human SCTR
other info2 :
Buffer: PBS with 0.02% sodium azide, pH 7.3
products categories :
Polyclonal
products description :
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.
ncbi pathways :
Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Class B/2 (Secretin Family Receptors) Pathway (106378); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class B Secretin-like Pathway (198781); Glucagon-type Ligand Receptors Pathway (106380)
ncbi summary :
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008]
uniprot summary :
SCTR: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family. Protein type: Receptor, GPCR; GPCR, family 2; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q14.1. Cellular Component: integral to plasma membrane; cytoplasmic microtubule; plasma membrane. Molecular Function: secretin receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; digestion; excretion