product summary
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company name :
MyBioSource
product type :
cDNA
product name :
RSPO2 cDNA Clone
catalog :
MBS1272438
quantity :
0.01 mg Plasmid + 0.
price :
165 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1272438
products type :
cDNA Clone
products full name :
RSPO2 cDNA Clone
products short name :
RSPO2
other names :
Homo sapiens R-spondin 2 homolog (Xenopus laevis), mRNA; R-spondin-2; R-spondin-2; R-spondin 2; Roof plate-specific spondin-2; hRspo2
products gene name :
RSPO2
other gene names :
RSPO2; RSPO2; CRISTIN2; hRspo2
uniprot entry name :
RSPO2_HUMAN
sequence length :
2498
sequence :
atgcgccagtatggagagtgcctgcattcctgcccatcc
gggtactatggacaccgagccccagatatgaacagatgt
gcaagatgcagaatagaaaactgtgattcttgctttagc
aaagacttttgtaccaagtgcaaagtaggcttttatttg
catagaggccgttgctttgatgaatgtccagatggtttt
gcaccattagaagaaaccatggaatgtgtggaaggatgt
gaagttggtcattggagcgaatggggaacttgtagcaga
aataatcgcacatgtggatttaaatggggtctggaaacc
agaacacggcaaattgttaaaaagccagtgaaagacaca
ataccgtgtccaaccattgctgaatccaggagatgcaag
atgacaatgaggcattgtccaggagggaagagaacacca
aaggcgaaggagaagaggaacaagaaaaagaaaaggaag
ctgatagaaagggcccaggagcaacacagcgtcttccta
gctacagacagagctaaccaataa
other info1 :
Vector: Please Inquire
ncbi gi num :
20380782
ncbi acc num :
BC027938
ncbi mol weight :
20,972 Da
ncbi summary :
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
uniprot summary :
R-spondin-2: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors. Belongs to the R-spondin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Cell development/differentiation. Chromosomal Location of Human Ortholog: 8q23.1. Cellular Component: extracellular region. Molecular Function: protein binding; receptor binding
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
165 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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