catalog number :
MBS127225
products full name :
LAMP1 Polyclonal Antibody
products short name :
LAMP1
products name syn :
LAMPA; CD107a; LGP120
other names :
Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane glycoprotein 1; lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1; lysosomal-associated membrane protein 1; CD107 antigen-like family member A; CD_antigen: CD107a
products gene name :
LAMP1
other gene names :
LAMP1; LAMP1; LAMPA; CD107a; LGP120; LAMP-1; Lysosome-associated membrane protein 1
uniprot entry name :
LAMP1_HUMAN
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human LAMP1. Calculated Molecular Weight: 44kDa
products categories :
Polyclonal
products description :
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
ncbi pathways :
Lysosome Pathway (99052); Lysosome Pathway (96865); Phagosome Pathway (153910); Phagosome Pathway (153859); Senescence And Autophagy Pathway (198780); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
uniprot summary :
LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 13q34. Cellular Component: integral to plasma membrane; lysosome; dendrite; multivesicular body; cell soma; membrane; late endosome; cytoplasm; plasma membrane; melanosome; endosome membrane; sarcolemma; external side of plasma membrane. Molecular Function: protein domain specific binding; protein binding; enzyme binding. Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; protein stabilization; viral reproduction; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity