BCHE cDNA Clone | MyBioSource MBS1271352 product information

product summary

company name :

MyBioSource

product type :

cDNA

product name :

BCHE cDNA Clone

catalog :

MBS1271352

quantity :

0.01 mg Plasmid + 0.

price :

175 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS1271352

products type :

cDNA Clone

products full name :

BCHE cDNA Clone

products short name :

BCHE

products name syn :

other names :

Homo sapiens butyrylcholinesterase, mRNA; Cholinesterase; cholinesterase; cholinesterase 1; choline esterase II; pseudocholinesterase; butyrylcholine esterase; acylcholine acylhydrolase; butyrylcholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II; Pseudocholinesterase

products gene name :

BCHE

other gene names :

BCHE; BCHE; E1; CHE1; CHE1

uniprot entry name :

CHLE_HUMAN

sequence length :

2173

sequence :

GGGATGAACTTGACAGTTTTTGGTGGCACGGTAACAGCCTTTCTTGGAATTCCCTATGCACA GCCACCTCTTGGTAGACTTCGATTCAAAAAGCCACAGTCTCTGACCAAGTGGTCTGATATTT GGAATGCCACAAAATATGCAAATTCTTGCTGTCAGAACATAGATCAAAGTTTTCCAGGCTTCCATGGATCAGAGATGTGGAACCCAAACACTGACCTCAGTGAAGACTGTTTATATCTAAATGTATGGATTCCAGCACCTAAACCAAAAAATGCCACTGTATTGATATGGATTTATGGTGGTGGTTT TCAAACTGGAACATCATCTTTACATGTTTATGATGGCAAGTTTCTGGCTCGGGTTGAAAGAG TTATTGTAGTGTCAATGAACTATAGGGTGGGTGCCCTAGGATTCTTAGCTTTGCCAGGAAATC CTGAGGCTCCAGGGAACATGGGTTTATTTGATCAACAGTTGGCTCTTCAGTGGGTTCAAAAA AATATAGCAGCCTTTGGTGGAAATCCTAAAAGTGTAACTCTCTTTGGAGAAAGTGCAGGAGC AGCTTCAGTTAGCCTGCATTTGCTTTCTCCTGGAAGCCATTCATTGTTCACCAGAGCCATTCT GCAAAGTGGATCCTTTAATGCTCCTTGGGCGGTAACATCTCTTTATGAAGCTAGGAACAGAA CGTTGAACTTAGCTAAATTGACTGGTTGCTCTAGAGAGAATGAGACTGAAATAATCAAGTGT CTTAGAAATAAAGATCCCCAAGAAATTCTTCTGAATGAAGCATTTGTTGTCCCCTATGGGAC TCCTTTGTCAGTAAACTTTGGTCCGACCGTGGATGGTGATTTTCTCACTGACATGCCAGACA TATTACTTGAACTTGGACAATTTAAAAAAACCCAGATTTTGGTGGGTGTTAATAAAGATGAA GGGACAGCTTTTTTAGTCTATGGTGCTCCTGGCTTCAGCAAAGATAACAATAGTATCATAACT AGAAAAGAATTTCAGGAAGGTTTAAAAATATTTTTTCCAGGAGTGAGTGAGTTTGGAAAGG AATCCATCCTTTTTCATTACACAGACTGGGTAGATGATCAGAGACCTGAAAACTACCGTGAG GCCTTGGGTGATGTTGTTGGGGATTATAATTTCATATGCCCTGCCTTGGAGTTCACCAAGAAGTTCTCAGAATGGGGAAATAATGCCTTTTTCTACTATTTTGAACACCGATCCTCCAAACTTCCGTGGCCAGAATGGATGGGAGTGATGCATGGCTATGAAATTGAATTTGTCTTTGGTTTACCTCTG GAAAGAAGAGATAATTACACAAAAGCCGAGGAAATTTTGAGTAGATCCATAGTGAAACGGT GGGCAAATTTTGCAAAATATGGGAATCCAAATGAGACTCAGAACAATAGCACAAGCTGGCC TGTCTTCAAAAGCACTGAACAAAAATATCTAACCTTGAATACAGAGTCAACAAGAATAATG ACGAAACTACGTGCTCAACAATGTCGATTCTGGACATCATTTTTTCCAAAAGTCTTGGAAATGACAGGAAATATTGATGAAGCAGAATGGGAGTGGAAAGCAGGATTCCATCGCTGGAACAATTACATGATGGACTGGAAAAATCAATTTAACGATTACACTAGCAAGAAAGAAAGTTGTGTGGGTC TCTAA
ATGCATAGCAAAGTCACAATCATATGCATCAGATTTCTC
TTTTGGTTTCTTTTGCTCTGCATGCTTATTGGGAAGTCA
CATACTGAAGATGACATCATAATTGCAACAAAGAATGGA
AAAGTCAGA

other info1 :

cDNA Size: 1809. Insert site: rrnB_T1, rrnB_T2. GeneID: 590. Vector: Please Inquire

products description :

Homo sapiens butyrylcholinesterase, mRNA complete cds.

ncbi gi num :

17390311

ncbi acc num :

BC018141

uniprot acc num :

P06276

ncbi mol weight :

68,418 Da

ncbi pathways :

Irinotecan Pathway (198905); Metabolism Of Proteins Pathway (106230); Peptide Hormone Metabolism Pathway (771603); Synthesis, Secretion, And Deacylation Of Ghrelin Pathway (119538)

ncbi summary :

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]

uniprot summary :

BCHE: Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency). BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait. Belongs to the type-B carboxylesterase/lipase family. Protein type: Nuclear envelope; Hydrolase; EC 3.1.1.8; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q26.1-q26.2. Cellular Component: membrane; endoplasmic reticulum lumen; nuclear envelope lumen; extracellular region. Molecular Function: choline binding; identical protein binding; enzyme binding; cholinesterase activity; beta-amyloid binding; acetylcholinesterase activity; catalytic activity. Biological Process: response to alkaloid; response to drug; negative regulation of cell proliferation; cellular protein metabolic process; cocaine metabolic process; choline metabolic process; response to folic acid; response to glucocorticoid stimulus; neuroblast differentiation; learning; negative regulation of synaptic transmission

size1 :

0.01 mg Plasmid + 0.2 mL Glycerol-Stock

price1 :

175 USD

more info or order :

MyBioSource product webpage