TEAD1 cDNA Clone | MyBioSource MBS1271077 product information

product summary

company name :

MyBioSource

product type :

cDNA

product name :

TEAD1 cDNA Clone

catalog :

MBS1271077

quantity :

0.01 mg Plasmid + 0.

price :

165 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS1271077

products type :

cDNA Clone

products full name :

TEAD1 cDNA Clone

products short name :

TEAD1

other names :

Homo sapiens TEA domain family member 1 (SV40 transcriptional enhancer factor), mRNA; Transcriptional enhancer factor TEF-1; transcriptional enhancer factor TEF-1; TEA domain transcription factor 1; NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13

products gene name :

TEAD1

other gene names :

TEAD1; TEAD1; AA; REF1; TCF13; TEF-1; NTEF-1; TCF-13; TEAD-1; TCF13; TEF1; TEAD-1; TCF-13

uniprot entry name :

TEAD1_HUMAN

sequence length :

3075

sequence :

ATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGAC
AATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAA
AGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGG
AGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTAT
GGTAGGAATGAATTGATAGCCAGATACATCAAACTCAGG
ACAGGCAAGACGAGGACCAGAAAACAGGTGTCTAGTCAC
ATTCAGGTTCTTGCCAGAAGGAAATCTCGTGATTTTCAT
TCCAAGCTAAAGGTAACAAGCATGGATCAGACTGCAAAG
GATAAGGCCCTGCAGCACATGGCGGCCATGTCCTCAGCC
CAGATCGTCTCGGCCACTGCCATTCATAACAAGCTGGGG
CTGCCTGGGATTCCACGCCCGACCTTCCCAGGGGCGCCG
GGGTTCTGGCCGGGAATGATTCAAACAGGGCAGCCAGGA
TCCTCACAAGACGTCAAGCCTTTTGTGCAGCAGGCCTAC
CCCATCCAGCCAGCGGTCACAGCCCCCATTCCAGGGTTT
GAGCCTGCATCGGCCCCAGCTCCCTCAGTCCCTGCCTGG
CAAGGTCGCTCCATTGGCACAACCAAGCTTCGCCTGGTG
GAATTTTCAGCTTTTCTCGAGCAGCAGCGAGACCCAGAC
TCGGCTGATTTAAACTGCAATATTCAAGATGATGCTGGG
GCTTTTTATGGTGTAACCAGTCAGTACGAGAGTTCTGAA
AATATGACAGTCACCTGTTCCACCAAAGTTTGCTCCTTT
GGGAAGCAAGTAGTAGAAAAAGTAGAGACGGAGTATGCA
AGGTTTGAGAATGGCCGATTTGTATACCGAATAAACCGC
TCCCCAATGTGTGAATATATGATCAACTTCATCCACAAG
CTCAAACACTTACCAGAGAAATATATGATGAACAGTGTT
TTGGAAAACTTCACAATTTTATTGGTGGTAACAAACAGG
GATACACAAGAAACTCTACTCTGCATGGCCTGTGTGTTT
GAAGTTTCAAATAGTGAACACGGAGCACAACATCATATT
TACAGGCTTGTAAAGGACTGA

other info1 :

Vector: Please Inquire

ncbi gi num :

133777908

ncbi acc num :

BC115398

ncbi mol weight :

40,000 Da

ncbi pathways :

Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway (576276)

ncbi summary :

This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]

uniprot summary :

TEAD1: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif. Interacts with YAP1 and WWTR1/TAZ. Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 11p15.2. Cellular Component: nucleoplasm. Molecular Function: DNA binding; protein binding; transcription factor activity. Biological Process: transcription initiation from RNA polymerase II promoter. Disease: Sveinsson Chorioretinal Atrophy

size1 :

0.01 mg Plasmid + 0.2 mL Glycerol-Stock

price1 :

165 USD

more info or order :

MyBioSource product webpage