catalog number :
MBS1269750
products type :
cDNA Clone
products full name :
LMX1A cDNA Clone
products short name :
LMX1A
other names :
Homo sapiens LIM homeobox transcription factor 1, alpha, mRNA; LIM homeobox transcription factor 1-alpha; LIM homeobox transcription factor 1-alpha; LIM homeobox transcription factor 1 alpha; LIM/homeobox protein 1.1; LMX-1.1; LIM/homeobox protein LMX1A
products gene name :
LMX1A
other gene names :
LMX1A; LMX1A; LMX1; LMX1.1; LMX-1.1
uniprot entry name :
LMX1A_HUMAN
sequence :
atggaaggaatcatgaacccctacacggctctgcccacc
ccacagcagctcctggccatcgagcagagtgtctacagc
tcagatcccttccgacagggtctcaccccaccccagatg
cctggagaccacatgcacccttatggtgccgagcccctt
ttccatgacctggatagcgacgacacctccctcagtaac
ctgggtgactgtttcctagcaacctcagaagctgggcct
ctgcagtccagagtgggaaaccccattgaccatctgtac
tccatgcagaattcttacttcacatcttga
other info1 :
Vector: Please Inquire
ncbi mol weight :
14,615 Da
ncbi summary :
This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
uniprot summary :
LMX1A: Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. 2 isoforms of the human protein are produced by alternative splicing. Protein type: DNA-binding; Cell development/differentiation; Motility/polarity/chemotaxis; Transcription factor. Chromosomal Location of Human Ortholog: 1q24.1. Molecular Function: protein binding. Biological Process: positive regulation of transcription from RNA polymerase II promoter
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock