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company name :
MyBioSource
product type :
cDNA
product name :
ABCB5 cDNA Clone
catalog :
MBS1269141
quantity :
10 ug Plasmid + 200
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1269141
products type :
cDNA Clone
products full name :
ABCB5 cDNA Clone
products short name :
ABCB5
other names :
Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 5, mRNA; ATP-binding cassette sub-family B member 5; ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5; ATP-binding cassette protein; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ABCB5 P-gp; P-glycoprotein ABCB5
products gene name :
ABCB5
other gene names :
ABCB5; ABCB5; ABCB5beta; EST422562; ABCB5alpha
uniprot entry name :
ABCB5_HUMAN
sequence length :
2784
sequence :
ATGGTGGATGAGAATGACATCAGAGCTTTAAATGTGCGG
CATTATCGAGACCATATTGGAGTGGTTAGTCAAGAGCCT
GTTTTGTTCGGGACCACCATCAGTAACAATATCAAGTAT
GGACGAGATGATGTGACTGATGAAGAGATGGAGAGAGCA
GCAAGGGAAGCAAATGCGTATGATTTTATCATGGAGTTT
CCTAATAAATTTAATACATTGGTAGGGGAAAAAGGAGCT
CAAATGAGTGGAGGGCAGAAACAGAGGATCGCAATTGCT
CGTGCCTTAGTTCGAAACCCCAAGATTCTGATTTTAGAT
GAGGCTACGTCTGCCCTGGATTCAGAAAGCAAGTCAGCT
GTTCAAGCTGCACTGGAGAAGGCGAGCAAAGGTCGGACT
ACAATCGTGGTAGCACACCGACTTTCTACTATTCGAAGT
GCAGATTTGATTGTGACCCTAAAGGATGGAATGCTGGCG
GAGAAAGGAGCACATGCTGAACTAATGGCAAAACGAGGT
CTATATTATTCACTTGTGATGTCACAGGATATTAAAAAA
GCTGATGAACAGATGGAGTCAATGACATATTCTACTGAA
AGAAAGACCAACTCACTTCCTCTGCACTCTGTGAAGAGC
ATCAAGTCAGACTTCATTGACAAGGCTGAGGAATCCACC
CAATCTAAAGAGATAAGTCTTCCTGAAGTCTCTCTATTA
AAAATTTTAAAGTTAAACAAGCCTGAATGGCCTTTTGTG
GTTCTGGGGACATTGGCTTCTGTTCTAAATGGAACTGTT
CATCCAGTATTTTCCATCATCTTTGCAAAAATTATAACC
ATGTTTGGAAATAATGATAAAACCACATTAAAGCATGAT
GCAGAAATTTATTCCATGATATTCGTCATTTTGGGTGTT
ATTTGCTTTGTCAGTTATTTCATGCAGGGATTATTTTAC
GGCAGAGCAGGGGAAATTTTAACGATGAGATTAAGACAC
TTGGCCTTCAAAGCCATGTTATATCAGGATATTGCCTGG
TTTGATGAAAAGGAAAACAGCACAGGAGGCTTGACAACA
ATATTAGCCATAGATATAGCACAAATTCAAGGAGCAACA
GGTTCCAGGATTGGCGTCTTAACACAAAATGCAACTAAC
ATGGGACTTTCAGTTATCATTTCCTTTATATATGGATGG
GAGATGACATTCCTGATTCTGAGTATTGCTCCAGTACTT
GCCGTGACAGGAATGATTGAAACCGCAGCAATGACTGGA
TTTGCCAACAAAGATAAGCAAGAACTTAAGCATGCTGGA
AAGATAGCAACTGAAGCTTTGGAGAATATACGTACTATA
GTGTCATTAACAAGGGAAAAAGCCTTCGAGCAAATGTAT
GAAGAGATGCTTCAGACTCAACACAGAAATACCTCGAAG
AAAGCACAGATTATTGGAAGCTGTTATGCATTCAGCCAT
GCCTTTATATATTTTGCCTATGCGGCAGGGTTTCGATTT
GGAGCCTATTTAATTCAAGCTGGACGAATGACCCCAGAG
GGCATGTTCATAGTTTTTACTGCAATTGCATATGGAGCT
ATGGCCATCGGAGAAACGCTCGTTTTGGCTCCTGAATAT
TCCAAAGCCAAATCGGGGGCTGCGCATCTGTTTGCCTTG
TTGGAAAAGAAACCAAATATAGACAGCCGCAGTCAAGAA
GGGAAAAAGCCAGACACATGTGAAGGGAATTTAGAGTTT
CGAGAAGTCTCTTTCTTCTATCCATGTCGCCCAGATGTT
TTCATCCTCCGTGGCTTATCCCTCAGTATTGAGCGAGGA
AAGACAGTAGCATTTGTGGGGAGCAGCGGCTGTGGGAAA
AGCACTTCTGTTCAACTTCTGCAGAGACTTTATGACCCC
GTGCAAGGACAAGTGCTGTTTGATGGTGTGGATGCAAAA
GAATTGAATGTACAGTGGCTCCGTTCCCAAATAGCAATC
GTTCCTCAAGAGCCTGTGCTCTTCAACTGCAGCATTGCT
GAGAACATCGCCTATGGTGACAACAGCCGTGTGGTGCCA
TTAGATGAGATCAAAGAAGCCGCAAATGCAGCAAATATC
CATTCTTTTATTGAAGGTCTCCCTGAGAAATACAACACA
CAAGTTGGACTGAAAGGAGCACAGCTTTCTGGCGGCCAG
AAACAAAGACTAGCTATTGCAAGGGCTCTTCTCCAAAAA
CCCAAAATTTTATTGTTGGATGAGGCCACTTCAGCCCTC
GATAATGACAGTGAGAAGGTGGTTCAGCATGCCCTTGAT
AAAGCCAGGACGGGAAGGACATGCCTAGTGGTCACTCAC
AGGCTCTCTGCAATTCAGAACGCAGATTTGATAGTGGTT
CTGCACAATGGAAAGATAAAGGAACAAGGAACTCATCAA
GAGCTCCTGAGAAATCGAGACATATATTTTAAGTTAGTG
AATGCACAGTCAGTGCAGTGA
other info1 :
Vector: pENTR223.1
ncbi gi num :
85397771
ncbi acc num :
BC104894
uniprot acc num :
Q2M3G0
ncbi mol weight :
89,832 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
uniprot summary :
Function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. Ref.1 Ref.10 Ref.11. Subcellular location: Cell membrane; Multi-pass membrane protein Ref.1. Tissue specificity: Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues. Ref.1 Ref.2. Miscellaneous: Depletion of ABCB5 by RNAi increases the sensitivity to several drugs of a subset of melanoma cells. Sequence similarities: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. [View classification]Contains 1 ABC transmembrane type-1 domain.Contains 2 ABC transporter domains. Caution: Was named ABCB1 by some authors. Sequence caution: The sequence AAN76500.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAQ03033.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
size :
10 ug Plasmid + 200 ul Glycerol Stock
price :
175 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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