product summary
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company name :
MyBioSource
product type :
antibody
product name :
MMP25 Polyclonal Antibody
catalog :
MBS126850
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS126850 image 1
Western blot analysis of extracts of various cell lines, using MMP25 antibody (MBS126850) at 1:400 dilution. Secondary antibody: HRP Goat Anti- Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST
image 2 :
MyBioSource MBS126850 image 2
Immunohistochemistry of paraffin-embedded human lung cancer using MMP25 antibody at dilution of 1:200 (40x lens).
image 3 :
MyBioSource MBS126850 image 3
Immunohistochemistry of paraffin-embedded human rectal cancer using MMP25 antibody at dilution of 1:200 (40x lens).
product information
catalog number :
MBS126850
products type :
Antibody
products full name :
MMP25 Polyclonal Antibody
products short name :
[MMP25]
products name syn :
[MMP20; MMPL1; MMP-25; MMP20A; MT6MMP; MTMMP6; MT-MMP6; MT6-MMP; MT-MMP 6]
other names :
[Matrix metalloproteinase-25; Matrix metalloproteinase-25; matrix metalloproteinase-25; leukolysin; matrix metalloproteinase 20; matrix metalloproteinase 25; matrix metallopeptidase-like 1; matrix metalloproteinase-like 1; membrane-type 6 matrix metalloproteinase; membrane-type matrix metalloproteinase 6; membrane-type-6 matrix metalloproteinase; matrix metallopeptidase 25; Leukolysin; Membrane-type matrix metalloproteinase 6; MT-MMP 6; MTMMP6; Membrane-type-6 matrix metalloproteinase; MT6-MMP; MT6MMP]
products gene name :
[MMP25]
other gene names :
[MMP25; MMP25; MMP20; MMPL1; MMP-25; MMP20A; MT6MMP; MTMMP6; MT-MMP6; MT6-MMP; MT-MMP 6; MMP20; MMPL1; MT6MMP; MMP-25; MT-MMP 6; MTMMP6; MT6-MMP; MT6MMP]
uniprot entry name :
MMP25_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
562
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
other info2 :
Immunogen: A synthetic peptide of human MMP25. Calculated MW: 62 kDa. Observed MW: 76 kDa.
products categories :
Polyclonal
products description :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
ncbi gi num :
12585274
ncbi acc num :
Q9NPA2.1
uniprot acc num :
Q9NPA2
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (576264); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Matrix Metalloproteinases Pathway (198900)
ncbi summary :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008]
uniprot summary :
MMP25: May activate progelatinase A. Belongs to the peptidase M10A family. Protein type: Membrane protein, integral; EC 3.4.24.-; Membrane protein, GPI anchor; Cell surface; Activator; Protease. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: proteinaceous extracellular matrix; membrane; plasma membrane; integral to membrane. Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding. Biological Process: hard palate development; proteolysis; inflammatory response
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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