catalog number :
MBS1268220
products type :
cDNA Clone
products full name :
AQP7 cDNA Clone
products short name :
AQP7
other names :
Homo sapiens aquaporin 7, mRNA; Aquaporin-7; aquaporin-7; aquaporin 7; Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like
products gene name :
AQP7
other gene names :
AQP7; AQP7; AQP7L; AQPap; GLYCQTL; AQP7L; AQP9; AQP-7; AQPap
uniprot entry name :
AQP7_HUMAN
sequence :
atggttctaaataaaaaatatgggagctaccttggtgtc
aacttgggttttggcttcggagtcaccatgggagtgcac
gtggcaggccgcatctctggagcccacatgaacgcagct
gtgacctttgctaactgtgcgctgggccgcgtgccctgg
aggaagtttccggtctatgtgctggggcagttcctgggc
tccttcctggcggctgccaccatctacagtctcttctac
acggccattctccacttttcgggtggacagctgatggtg
accggtcccgtcgctacagctggcatttttgccacctac
cttcctgatcacatgacattgtggcggggcttcctgaat
gaggcgtggctgaccgggatgctccagctgtgtctcttc
gccatcacggaccaggagaacaacccagcactgccagga
acagaggcgctggtgataggcatcctcgtggtcatcatc
ggggtgtcccttggcatgaacacaggatatgccatcaac
ccgtcccgggacctgcccccccgcatcttcaccttcatt
gctggttggggcaaacaggtcttcaggtggcatcatcta
cctggtcttcattggctccaccatcccacgggagcccct
gaaattggaggattctgtggcgtatga
other info1 :
Vector: Please Inquire
ncbi mol weight :
17,954 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (187187); Integrated Breast Cancer Pathway (219801); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Passive Transport By Aquaporins Pathway (187188); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glycerol From Adipocytes To The Liver By Aquaporins Pathway (187190)
ncbi summary :
This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015]
uniprot summary :
AQP7: Forms a channel for water and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Transporter, aquaporin family; Transporter; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 9p13. Cellular Component: cytoplasm; integral to plasma membrane; intercellular junction; plasma membrane. Molecular Function: glycerol channel activity; urea transmembrane transporter activity; water channel activity. Biological Process: cellular water homeostasis; excretion; generation of precursor metabolites and energy; glycerol transport; water transport. Disease: Glycerol Quantitative Trait Locus
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock