product summary
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company name :
MyBioSource
product type :
antibody
product name :
SETD1B Polyclonal Antibody
catalog :
MBS126717
quantity :
0.05 mL
price :
235 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using SETD1B antibody (MBS126717). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
product information
catalog number :
MBS126717
products type :
Antibody
products full name :
SETD1B Polyclonal Antibody
products short name :
[SETD1B]
products name syn :
[KMT2G; Set1B]
other names :
[Histone-lysine N-methyltransferase SETD1B; Histone-lysine N-methyltransferase SETD1B; histone-lysine N-methyltransferase SETD1B; hSET1B; lysine N-methyltransferase 2G; SET domain-containing protein 1B; SET domain containing 1B; Lysine N-methyltransferase 2G; SET domain-containing protein 1B; hSET1B]
products gene name :
[SETD1B]
other gene names :
[SETD1B; SETD1B; KMT2G; Set1B; KIAA1076; KMT2G; SET1B; hSET1B]
uniprot entry name :
SET1B_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
1966
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
WB: 1:200 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:20 - 1:50
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: Recombinant protein of human SETD1B. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007)
ncbi gi num :
597439633
ncbi acc num :
Q9UPS6.3
uniprot acc num :
Q9UPS6
ncbi mol weight :
Calculated MW: 208kDa/212kDa. Observed MW: 263kDa
ncbi pathways :
Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); Lysine Degradation Pathway (82956); Lysine Degradation Pathway (320); PKMTs Methylate Histone Lysines Pathway (1127686)
ncbi summary :
SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008]
uniprot summary :
SETD1B: Histone methyltransferase that specifically methylates Lys-4 of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring Lys- 9 residue is already methylated. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates Lys-4 of histone H3 in vitro. Protein type: Methyltransferase, protein lysine; Methyltransferase; Amino Acid Metabolism - lysine degradation; EC 2.1.1.43. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: nucleoplasm; histone methyltransferase complex; cytoplasm; nuclear speck; chromosome. Molecular Function: protein binding; histone lysine N-methyltransferase activity (H3-K4 specific); RNA binding; nucleotide binding. Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of transcription, DNA-dependent; histone H3-K4 methylation
size1 :
0.05 mL
price1 :
235 USD
size2 :
0.1 mL
price2 :
350
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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