product summary
Loading...
company name :
MyBioSource
product type :
cDNA
product name :
ZEB2 cDNA Clone
catalog :
MBS1267079
quantity :
0.01 mg Plasmid + 0.
price :
1185 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1267079
products type :
cDNA Clone
products full name :
ZEB2 cDNA Clone
products short name :
ZEB2
other names :
Homo sapiens zinc finger E-box binding homeobox 2, mRNA; Zinc finger E-box-binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger E-box binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b
products gene name :
ZEB2
other gene names :
ZEB2; ZEB2; SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; KIAA0569; SIP1; ZFHX1B; ZFX1B; SMADIP1
uniprot entry name :
ZEB2_HUMAN
sequence length :
3912
sequence :
ATGAAGCAGCCGATCATGGCGGATGGCCCCCGGTGCAAG
AGGCGCAAACAAGCCAATCCCAGGAGGAAAAACGTGGTG
AACTATGACAATGTAGTGGACACAGGTTCTGAAACAGAT
GAGGAAGACAAGCTTCATATTGCTGAGGATGACGGTATT
GCCAACCCTCTGGACCAGGAGACGAGTCCAGCTAGTGTG
CCCAACCATGAGTCCTCCCCACACGTGAGCCAAGCTCTG
TTGCCAAGAGAGGAAGAGGAAGATGAAATAAGGGAGGGT
GGAGTGGAACACCCCTGGCACAACAACGAGATTCTACAA
GCCTCTGTAGATGGTCCAGAAGAAATGAAGGAAGACTAT
GACACTATGGGGCCAGAAGCCACGATCCAGACCGCAATT
AACAATGGTACAGTGAAGAATGCAAATTGCACATCAGAT
TTTGAGGAATACTTTGCCAAAAGAAAACTGGAGGAACGC
GATGGTCATGCAGTCAGCATCGAGGAGTACCTTCAGCGC
AGTGACACAGCCATTATTTACCCAGAAGCCCCTGAGGAG
CTGTCTCGCCTTGGCACGCCAGAGGCCAATGGGCAAGAA
GAAAATGACCTGCCACCTGGAACTCCAGATGCTTTTGCC
CAACTGCTGACCTGCCCCTACTGCGACCGGGGCTACAAG
CGCTTGACATCACTGAAGGAGCACATCAAGTACCGCCAC
GAGAAGAATGAAGAGAACTTTTCCTGCCCTCTCTGTAGC
TACACGTTTGCCTACCGCACCCAGCTCGAGCGGCATATG
GTGACACACAAGCCAGGGACAGATCAGCACCAAATGCTA
ACCCAAGGAGCAGGTAATCGCAAGTTCAAATGCACAGAG
TGTGGCAAGGCCTTCAAATATAAACACCATCTGAAAGAA
CACCTGCGAATTCACAGTGGTGAAAAACCTTACGAGTGC
CCAAACTGCAAGAAACGTTTCTCCCATTCTGGTTCCTAC
AGTTCGCACATCAGCAGCAAGAAATGTATTGGTTTAATC
TCTGTAAATGGCCGAATGAGAAACAATATCAAGACGGGT
TCTTCCCCTAATTCTGTTTCTTCTTCTCCTACTAATTCA
GCCATTACCCAGTTAAGAAACAAGTTGGAGAATGGAAAA
CCACTTAGTATGTCTGAACAGACAGGCTTACTTAAAATT
AAAACAGAACCACTAGACTTCAATGACTATAAAGTTCTT
ATGGCTACACACGGGTTTAGTGGCACTAGTCCCTTTATG
AATGGTGGGCTTGGAGCCACCAGCCCTTTAGGAGTTCAT
CCATCTGCTCAGAGTCCAATGCAGCACTTAGGTGTAGGG
ATGGAAGCCCCTTTACTTGGGTTTCCCACCATGAATAGT
AATTTAAGTGAGGTACAAAAGGTTCTACAGATTGTGGAC
AATACTGTTTCCAGGCAAAAAATGGACTGCAAGGCTGAA
GAAATTTCAAAGTTGAAAGGTTATCACATGAAGGATCCA
TGCTCTCAACCTGAGGAACAAGGAGTTACTTCTCCTAAT
ATTCCGCCTGTCGGTCTTCCGGTAGTGAGTCATAATGGT
GCCACTAAAAGTATTATTGACTATACGTTGGAAAAAGTC
AATGAAGCCAAAGCTTGCCTCCAGAGCTTGACTACTGAC
TCAAGGAGACAGATCAGTAATATAAAGAAAGAGAAGCTA
CGTACTTTAATAGATTTGGTCACTGATGACAAAATGATT
GAGAACCACAACATATCCACTCCATTTTCATGCCAGTTC
TGTAAAGAAAGTTTTCCTGGCCCCATCCCTTTGCATCAG
CATGAACGTTACCTTTGTAAGATGAATGAAGAGATCAAG
GCGGTCCTGCAGCCTCATGAAAACATAGTCCCCAACAAA
GCCGGAGTTTTTGTTGATAATAAAGCCCTCCTCTTGTCA
TCTGTACTTTCTGAGAAAGGAATGACAAGCCCCATCAAC
CCATACAAGGACCACATGTCTGTACTCAAAGCATACTAT
GCTATGAACATGGAGCCCAACTCCGATGAACTGCTGAAA
ATTTCCATTGCTGTGGGCCTTCCTCAGGAATTTGTGAAG
GAATGGTTTGAACAACGAAAAGTCTACCAGTACTCAAAT
TCCAGGTCCCCATCCCTGGAAAGAAGCTCCAAGCCGTTA
GCTCCCAACAGTAACCCTCCCACAAAAGACTCTTTATTA
CCCAGGTCTCCTGTAAAACCTATGGACTCCATAACATCA
CCATCTATAGCAGAACTCCACAACAGTGTTACGAATTGT
GATCCTCCTCTCAGGCTAACAAAACCTTCCCATTTTACC
AATATTAAACCAGTTGAAAAATTGGACCACTCCAGGAGT
AATACTCCTTCTCCCTTAAATCTTTCCTCCACATCTTCT
AAAAACTCCCACAGTAGTTCATACACTCCAAACAGCTTC
TCTTCTGAGGAGCTCCAGGCTGAGCCTTTAGACTTGTCA
TTACCAAAACAAATGAAAGAACCCAAAAGTATTATAGCC
ACAAAGAACAAAACAAAAGCTAGTAGCATCAGTTTAGAT
CATAACAGTGTTTCTTCCTCATCTGAAAACTCAGATGAG
CCTCTGAACTTGACTTTTATCAAGAAGGAATTTTCAAAT
TCAAATAATCTGGACAACAAAAGCACTAACCCAGTGTTC
AGCATGAACCCATTTAGTGCCAAACCTTTATACACAGCT
CTTCCACCTCAAAGCGCATTTCCCCCTGCTACTTTCATG
CCACCAGTCCAGACCAGTATTCCTGGGCTACGACCATAC
CCAGGACTGGATCAGATGAGCTTCCTACCACATATGGCC
TACACCTACCCAACTGGAGCAGCTACTTTTGCTGATATG
CAGCAAAGGAGAAAGTACCAGCGGAAACAAGGATTTCAG
GGAGAATTGCTTGATGGAGCACAAGACTACATGTCAGGC
CTAGATGATATGACAGACTCCGACTCCTGTCTGTCTCGC
AAAAAGATCAAGAAGACAGAGAGTGGCATGTATGCATGT
GACTTATGTGACAAGACATTCCAGAAAAGCAGTTCCCTT
CTGCGACATAAATACGAACACACAGGAAAAAGACCACAT
CAGTGTCAGATTTGTAAGAAAGCGTTTAAACACAAGCAC
CACCTTATCGAGCACTCAAGGCTTCACTCGGGCGAGAAG
CCCTATCAGTGTGATAAATGTGGCAAGCGCTTCTCACAC
TCGGGCTCGTACTCGCAGCACATGAATCACAGGTATTCC
TACTGCAAGCGGGAGGCGGAGGAGCGGGAAGCGGCGGAG
CGCGAGGCGCGCGAGAAAGGGCACTTGGAACCCACCGAG
CTGCTGATGAACCGGGCTTACTTGCAGAGCATTACCCCT
CAGGGGTACTCTGACTCGGAGGAGAGGGAGAGTATGCCG
AGGGATGGCGAGAGCGAGAAGGAGCACGAGAAAGAAGGC
GAGGATGGCTACGGGAAGCTGGGCAGACAGGATGGCGAC
GAGGAGTTCGAGGAGGAAGAGGAAGAAAGTGAAAATAAA
AGTATGGATACGGATCCCGAAACGATACGAGATGAAGAA
GAGACTGGAGATCACTCCATGGACGATAGTTCGGAGGAT
GGGAAAATGGAAACCAAATCAGACCACGAGGAAGACAAT
ATGGAAGATGGCATGTAA
other info1 :
Vector: Please Inquire
ncbi gi num :
117558785
ncbi acc num :
BC127102
ncbi mol weight :
133,806 Da
ncbi pathways :
TGF Beta Signaling Pathway (198810); TGF-beta Receptor Signaling Pathway (198774)
ncbi summary :
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
uniprot summary :
ZEB2: Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin. Defects in ZEB2 are the cause of Mowat-Wilson syndrome (MWIS); also known as Hirschsprung disease-mental retardation syndrome. A complex developmental disorder characterized by mental retardation, delayed motor development, epilepsy, microcephaly and a wide spectrum of clinically heterogeneous features suggestive of neurocristopathies at the cephalic, cardiac, and vagal levels. Some patients manifest Hirschsprung disease. Affected patients show an easily recognizable facial appearance with deep set eyes and hypertelorism, medially divergent, broad eyebrows, prominent columella, pointed chin and uplifted, notched ear lobes. Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family. Protein type: Transcription, coactivator/corepressor; Motility/polarity/chemotaxis; DNA-binding; C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 2q22.3. Cellular Component: nucleus. Molecular Function: protein binding. Biological Process: negative regulation of transcription from RNA polymerase II promoter; pigmentation during development; positive regulation of melanin biosynthetic process; positive regulation of melanocyte differentiation; positive regulation of transcription from RNA polymerase II promoter. Disease: Mowat-wilson Syndrome
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
1185 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!