cDNA

TEAD4 cDNA Clone

MBS1267011

0.01 mg Plasmid + 0.

165 USD

cDNA Clone

TEAD4 cDNA Clone

TEAD4

Homo sapiens TEA domain family member 4, mRNA; Transcriptional enhancer factor TEF-3; transcriptional enhancer factor TEF-3; TEA domain transcription factor 4; TEA domain family member 4; TEAD-4; Transcription factor 13-like 1; Transcription factor RTEF-1

TEAD4

TEAD4; TEAD4; TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; TCF13L1; hRTEF-1B; RTEF1; TCF13L1; TEF3; TEAD-4

TEAD4_HUMAN

1702

atgtatggtcggaacgagctgattgcccgctacatcaag
ctccggacagggaagacccgcaccaggaagcaggtctcc
agccacatccaggtgctggctcgtcgcaaagctcgcgag
atccaggccaagctaaaggaccaggcagctaaggacaag
gccctgcagagcatggctgccatgtcgtctgcacagatc
atctccgccacggccttccacagtagcatggccctcgcc
cggggccccggccgcccagcagtctcagggttttggcaa
ggagctttgccaggccaagccggaacgtcccatgatgtg
aagcctttctctcagcaaacctatgctgtccagcctccg
ctgcctctgccagggtttgagtctcctgcagggcccgcc
ccatcgccctctgcgcccccggcacccccatggcagggc
cgcagcgtggccagctccaagctctggatgttggagttc
tctgccttcctggagcagcagcaggacccggacacgtac
aacaagcacctgttcgtgcacattggccagtccagccca
agctacagcgacccctacctcgaagccgtggacatccgc
caaatctatgacaaattcccggagaaaaagggtggactc
aaggatctcttcgaacggggaccctccaatgcctttttt
cttgtgaagttctgggcagacctcaacaccaacatcgag
gatgaaggcagctccttctatggggtctccagccagtat
gagagccccgagaacatgatcatcacctgctccacgaag
gtctgctctttcggcaagcaggtggtggagaaagttgag
acagagtatgctcgctatgagaatggacactactcttac
cgcatccaccggtccccgctctgtgagtacatgatcaac
ttcatccacaagctcaagcacctccctgagaagtacatg
atgaacagcgtgctggagaacttcaccatcctgcaggtg
gtcaccaacagagacacacaggagaccttgctgtgcatt
gcctatgtctttgaggtgtcagccagtgagcacggggct
cagcaccacatctacaggctggtgaaagaatga

Vector: Please Inquire

15930110

BC015497

44,058 Da

Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway (576276)

This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]

TEAD4: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. 2 isoforms of the human protein are produced by alternative splicing. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 12p13.3-p13.2. Cellular Component: nucleoplasm. Molecular Function: protein binding; transcription factor activity. Biological Process: muscle development; positive regulation of defense response to virus by host; regulation of transcription from RNA polymerase II promoter; skeletal development; transcription initiation from RNA polymerase II promoter

0.01 mg Plasmid + 0.2 mL Glycerol-Stock

165 USD