product summary
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company name :
MyBioSource
product type :
cDNA
product name :
TNFRSF14 cDNA Clone
catalog :
MBS1266815
quantity :
0.01 mg Plasmid + 0.
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1266815
products type :
cDNA Clone
products full name :
TNFRSF14 cDNA Clone
products short name :
TNFRSF14
other names :
Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), mRNA; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily member 14; CD40-like protein; herpesvirus entry mediator A; herpes virus entry mediator A; tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); tumor necrosis factor receptor superfamily, member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2
products gene name :
TNFRSF14
other gene names :
TNFRSF14; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; HVEA; HVEM; Herpesvirus entry mediator A; HveA; TR2
uniprot entry name :
TNR14_HUMAN
sequence length :
1612
sequence :
ATGGAGCCTCCTGGAGACTGGGGGCCTCCTCCCTGGAGA
TCCACCCCCAGAACCGACGTCTTGAGGCTGGTGCTGTAT
CTCACCTTCCTGGGAGCCCCCTGCTACGCCCCAGCTCTG
CCGTCCTGCAAGGAGGACGAGTACCCAGTGGGCTCCGAG
TGCTGCCCCAAGTGCAGTCCAGGTTATCGTGTGAAGGAG
GCCTGCGGGGAGCTGACGGGCACAGTGTGTGAACCCTGC
CCTCCAGGCACCTACATTGCCCACCTCAATGGCCTAAGC
AAGTGTCTGCAGTGCCAAATGTGTGACCCAGCCATGGGC
CTGCGCGCGAGCCGGAACTGCTCCAGGACAGAGAACGCC
GTGTGTGGCTGCAGCCCAGGCCACTTCTGCATCGTCCAG
GACGGGGACCACTGCGCCGCGTGCCGCGCTTACGCCACC
TCCAGCCCGGGCCAGAGGGTGCAGAAGGGAGGCACCGAG
AGTCAGGACACCCTGTGTCAGAACTGCCCCCCGGGGACC
TTCTCTCCCAATGGGACCCTGGAGGAATGTCAGCACCAG
ACCAAGTGCAGCTGGCTGGTGACGAAGGCCGGAGCTGGG
ACCAGCAGCTCCCACTGGGTATGGTGGTTTCTCTCAGGG
AGCCTCGTCATCGTCATTGTTTGCTCCACAGTTGGCCTA
ATCATATGTGTGAAAAGAAGAAAGCCAAGGGGTGATGTA
GTCAAGGTGATCGTCTCCGTCCAGCGGAAAAGACAGGAG
GCAGAAGGTGAGGCCACAGTCATTGAGGCCCTGCAGGCC
CCTCCGGACGTCACCACGGTGGCCGTGGAGGAGACAATA
CCCTCATTCACGGGGAGGAGCCCAAACCACTGA
other info1 :
Vector: Please Inquire. Accession Number: BC002794. cDNA Size: 852. Recombination site: attL1, attL2. Gene ID: 8764
products description :
Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), mRNA (cDNA clone MGC:3753 IMAGE:3614650), complete cds.
ncbi gi num :
33877193
ncbi acc num :
BC002794
uniprot acc num :
Q92956
ncbi mol weight :
30,392 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Costimulation By The CD28 Family Pathway (119552); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Immune System Pathway (106386)
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008]
uniprot summary :
TNFRSF14: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. Protein type: Membrane protein, integral; Receptor, misc.; Cell cycle regulation. Chromosomal Location of Human Ortholog: 1p36.32. Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: viral receptor activity; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding. Biological Process: positive regulation of peptidyl-tyrosine phosphorylation; entry of virus into host cell; defense response to Gram-positive bacterium; cell surface receptor linked signal transduction; tumor necrosis factor-mediated signaling pathway; T cell costimulation; positive regulation of cytokine secretion during immune response; negative regulation of alpha-beta T cell proliferation; immune response; defense response to Gram-negative bacterium
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock
price1 :
175 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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