catalog number :
MBS1266236
products type :
cDNA Clone
products full name :
TRPM1 cDNA Clone
products short name :
TRPM1
other names :
Homo sapiens transient receptor potential cation channel, subfamily M, member 1, mRNA; Transient receptor potential cation channel subfamily M member 1; transient receptor potential cation channel subfamily M member 1; transient receptor potential cation channel subfamily M member 1; Long transient receptor potential channel 1; LTrpC1; Melastatin-1
products gene name :
TRPM1
other gene names :
TRPM1; TRPM1; MLSN1; CSNB1C; LTRPC1; LTrpC1
uniprot entry name :
TRPM1_HUMAN
sequence :
atgaaagactctaacaggtgttgctgtggccagttcacc
aaccagcatatcccccctctgccaagtgcaacacccagc
aaaaatgaagaggaaaacaaacaggtggagactcagcct
gagaaatggtctgttgccaagcacacccagagctaccca
acagattcctatggagttcttgaattccagggtggcgga
tattccaataaagccatggtgagaaaggcattcagacat
ggtgccactaggatcacagctttcattggcggccagtct
cccagccccaaactgcagatacctggtcttcttcatggc
tgtggctcaatcttcctagatatttcattgaaaaaccaa
gagatatatctgtgcacatggcttttagccatgaggctt
ggaaactggacaccactgtaa
other info1 :
Vector: Please Inquire
ncbi mol weight :
15,099 Da
ncbi summary :
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
uniprot summary :
TRPM1: a transient receptor potential (TRP) ion channel. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Its expression is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis. Protein type: Membrane protein, integral; Channel, calcium; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 15q13.3. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: calcium channel activity. Biological Process: metabotropic glutamate receptor signaling pathway; transport; visual perception. Disease: Night Blindness, Congenital Stationary, Type 1c
size1 :
0.01 mg Plasmid + 0.2 mL Glycerol-Stock