product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rabies virus (strain ERA) (RABV) Glycoprotein G
catalog :
MBS1265619
quantity :
0.05 mg (E-Coli)
price :
180 USD
more info or order :
product information
catalog number :
MBS1265619
products type :
Recombinant Protein
products full name :
Recombinant Rabies virus (strain ERA) (RABV) Glycoprotein G
products short name :
Glycoprotein G
other names :
Glycoprotein; Glycoprotein
products gene name :
G
other gene names :
G
uniprot entry name :
GLYCO_RABVE
host :
E Coli
sequence positions :
20-459; Virion surface domain.
sequence length :
459
sequence :
KFPIYTILDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLS
GFSYMELKVGYILAIKMNGFTCTGVVTEAETYTNFVGYV
TTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYP
DYRWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPS
GKCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNS
RGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLR
LMDGTWVAMQTSNETKWCPPDQLVNLHDFRSDEIEHLVV
EELVRKREECLDALESIMTTKSVSFRRLSHLRKLVPGFG
KAYTIFNKTLMEADAHYKSVRTWNEILPSKGCLRVGGRC
HPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLES
SVIPLVHPLADPSTVFKDGDEAEDFVEVHLPDVHNQVSG
VDLGLPNWGKY
purity :
Greater than 90% as determined by SDS-PAGE.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
products references :
Structure of the glycoprotein gene in rabies virus.Anilionis A., Wunner W.H., Curtis P.J.Nature 294:275-278(1981) Amino acid sequence of the rabies virus glycoprotein deduced from its cloned gene.Anilionis A., Wunner W.H., Curtis P.J.Comp. Immunol. Microbiol. Infect. Dis. 5:27-32(1982) Complete nucleotide sequencing of SAD derivatives of attenuated rabies virus vaccine strains.Geue L., Schares S., Schnick C., Kliemt J., Beckert A., Hoffmann B., Freuling C., Marston D., McElhinney L., Fooks A., Zanoni R., Peterhans E., Cox J.H., Mueller T. Antigenic variants of CVS rabies virus with altered glycosylation sites.Wunner W.H., Dietzschold B., Smith C.L., Lafon M., Golub E.Virology 140:1-12(1985) N-linked glycosylation of rabies virus glycoprotein. Individual sequons differ in their glycosylation efficiencies and influence on cell surface expression.Shakin-Eshleman S.H., Remaley A.T., Eshleman J.R., Wunner W.H., Spitalnik S.L.J. Biol. Chem. 267:10690-10698(1992) The role of site-specific N-glycosylation in secretion of soluble forms of rabies virus glycoprotein.Wojczyk B.S., Stwora-Wojczyk M., Shakin-Eshleman S.H., Wunner W.H., Spitalnik S.L.Glycobiology 8:121-130(1998) Rabies virus receptors.Lafon M.J. Neurovirol. 11:82-87(2005)
ncbi gi num :
138301
ncbi acc num :
P03524.1
uniprot acc num :
P03524
ncbi mol weight :
53.6kD
size1 :
0.05 mg (E-Coli)
price1 :
180 USD
size2 :
0.2 mg (E-Coli)
price2 :
490
size3 :
0.5 mg (E-Coli)
price3 :
715
size4 :
1 mg (E-Coli)
price4 :
1170
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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