product summary
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company name :
MyBioSource
product type :
antibody
product name :
SPINK1 Polyclonal Antibody
catalog :
MBS126556
quantity :
0.05 mL
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS126556
products type :
Antibody
products full name :
SPINK1 Polyclonal Antibody
products short name :
SPINK1
products name syn :
SPINK1; PCTT; PSTI; Spink3; TATI; TCP
other names :
Pancreatic secretory trypsin inhibitor; Pancreatic secretory trypsin inhibitor; pancreatic secretory trypsin inhibitor; tumor-associated trypsin inhibitor; serine protease inhibitor, Kazal type 1; serine peptidase inhibitor, Kazal type 1; Serine protease inhibitor Kazal-type 1; Tumor-associated trypsin inhibitor; TATI
products gene name :
SPINK1
other gene names :
SPINK1; SPINK1; TCP; PCTT; PSTI; TATI; Spink3; PSTI; TATI
uniprot entry name :
ISK1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
79
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human SPINK1. Calculated Molecular Weight: 9kDa
products categories :
Polyclonal
products description :
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
ncbi gi num :
124856
ncbi acc num :
P00995.2
uniprot acc num :
P00995
ncbi mol weight :
79
ncbi pathways :
Prostate Cancer Pathway (755440)
ncbi summary :
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
uniprot summary :
SPINK1: This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). TCP is an idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much younger age of onset, pancreatic calcification, a high incidence of insulin dependent but ketosis resistant diabetes mellitus, and an exceptionally high incidence of pancreatic cancer. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q32. Cellular Component: extracellular space. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; endopeptidase inhibitor activity. Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; regulation of acrosome reaction. Disease: Tropical Calcific Pancreatitis; Pancreatitis, Hereditary
size1 :
0.05 mL
price1 :
230 USD
size2 :
0.1 mL
price2 :
305
size3 :
0.2 mL
price3 :
460
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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