product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
catalog :
MBS1265516
quantity :
0.05 mg (E-Coli)
price :
180 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1265516
products type :
Recombinant Protein
products full name :
Recombinant Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
products short name :
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
products name syn :
Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
other names :
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat and Ig domain containing 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
products gene name :
Lingo1
products gene name syn :
Lern1; Lrrn6a
other gene names :
Lingo1; Lingo1; LERN1; Lrrn6a; UNQ201; LINGO-1; AV148400; 4930471K13Rik; Lern1; Lrrn6a
uniprot entry name :
LIGO1_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
37-555,Partial,Provide the complete extracellular domain.
sequence length :
555
sequence :
CPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGK
NRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLF
NLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVIL
LDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLT
LEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFK
RLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNL
TAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQ
EIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEES
AFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQ
QPTCATPEFVQGKEFKDFPDVLLPNYFTCRRAHIRDRKA
QQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKS
NGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMP
AHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATV
PFPFDIKTLIIAT
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 1 Publication
ncbi gi num :
901694051
ncbi acc num :
NP_001298005.1
ncbi gb acc num :
NM_001311076.1
uniprot acc num :
Q9D1T0
ncbi mol weight :
60.8kD
ncbi pathways :
Axonal Growth Inhibition (RHOA Activation) Pathway (1324627); Signal Transduction Pathway (1324550); Signalling By NGF Pathway (1324614); MRNA Processing Pathway (198369); P75 NTR Receptor-mediated Signalling Pathway (1324616); P75NTR Regulates Axonogenesis Pathway (1324625)
uniprot summary :
LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: integral to membrane; membrane; plasma membrane. Molecular Function: epidermal growth factor receptor binding; protein binding. Biological Process: axonogenesis; central nervous system neuron development; negative regulation of oligodendrocyte differentiation; neurite development; protein kinase B signaling cascade
size1 :
0.05 mg (E-Coli)
price1 :
180 USD
size2 :
0.05 mg (Yeast)
price2 :
260
size3 :
0.2 mg (E-Coli)
price3 :
490
size4 :
0.2 mg (Yeast)
price4 :
600
size5 :
0.5 mg (E-Coli)
price5 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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