protein

Recombinant Human Metallothionein-1A protein

MBS1265290

0.05 mg (E-Coli)

190 USD

Recombinant Protein

Recombinant Human Metallothionein-1A protein

Metallothionein-1A

Metallothionein-IA; MT-IA

metallothionein-1A; Metallothionein-1A; metallothionein-1A; metallothionein 1A; Metallothionein-IA; MT-IA

MT1A

MT1S; 1A

MT1A; MT1A; MT1; MTC; MT1S; MT1S; MT-1A; MT-IA

MT1A_HUMAN

E Coli

Jan-59

61

MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPM
SCAKCAQGCICKGASEKCSC

Greater than 90% as determined by SDS-PAGE.

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Epigenetics and Nuclear Signaling

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

Structural and functional analysis of the human metallothionein-IA gene differential induction by metal ions and glucocorticoids.Richards R.I., Heguy A., Karin M.Cell 37:263-272(1984) Cloning of a novel member of the MT gene family - MT1S.Wang J., Zheng L., Yu L.The sequence and analysis of duplication-rich human chromosome 16.Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.Nature 432:988-994(2004)

71274113

NP_005937.2

NM_005946.2

P04731

33.3kD

Metabolism Pathway (1269956); Metallothioneins Bind Metals Pathway (1339158); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Response To Metal Ions Pathway (1339157)

MT1: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm. Molecular Function: protein binding; zinc ion binding. Biological Process: negative regulation of growth; response to metal ion

0.05 mg (E-Coli)

190 USD

0.2 mg (E-Coli)

460

0.5 mg (E-Coli)

750

1 mg (E-Coli)

1180