catalog number :
MBS1265255
products type :
Recombinant Protein
products full name :
Recombinant Human Metallothionein-2
products short name :
Metallothionein-2
products name syn :
Metallothionein-2A; Metallothionein-II; MT-II
other names :
metallothionein-2; Metallothionein-2; metallothionein-2; metallothionein 2A; Metallothionein-2A; Metallothionein-II; MT-II
products gene name :
MT2A
products gene name syn :
CES1; MT2
other gene names :
MT2A; MT2A; MT2; CES1; MT2; MT-2; MT-II
uniprot entry name :
MT2_HUMAN
sequence positions :
Jan-59
sequence :
MDPNCSCAAGDSCTCAGSCKCKECKCTSCKKSCCSCCPV
GCAKCAQGCICKGASDKCSC
purity :
Greater than 90% as determined by SDS-PAGE.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Epigenetics and Nuclear Signaling
products description :
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
products references :
Primary structure of human hepatic metallothionein.Kissling M.M., Kaegi J.H.R.FEBS Lett. 82:247-250(1977)
ncbi acc num :
NP_005944.1
ncbi gb acc num :
NM_005953.3
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Immune System Pathway (1269170); Interferon Signaling Pathway (1269311); Interferon Gamma Signaling Pathway (1269314); Metabolism Pathway (1269956); Metallothioneins Bind Metals Pathway (1339158); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Response To Metal Ions Pathway (1339157)
uniprot summary :
MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm. Molecular Function: drug binding; protein binding; zinc ion binding. Biological Process: cellular copper ion homeostasis; cytokine and chemokine mediated signaling pathway; negative regulation of growth; response to metal ion