product summary
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company name :
MyBioSource
product type :
antibody
product name :
Bim
catalog :
MBS126525
quantity :
0.1 mL
price :
275 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS126525 image 1
Western blot analysis of extracts of various cell lines, using BCL2L11 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS126525
products type :
Antibody
products full name :
Bim
products short name :
[Bim]
products name syn :
[BCL2L11; Bim]
other names :
[bcl-2-like protein 11 isoform 11; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death]
other gene names :
[BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11]
uniprot entry name :
B2L11_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
108
purity :
Affinity purification
storage stability :
Store at 4 degree C. Avoid freeze / thaw cycles.
tested application :
WB, IHC, FC
app notes :
WB 1:500 - 1:1000. IHC 1:20 - 1:50. FC 1:20 - 1:50
image1 heading :
Western Blot (WB)
other info1 :
Category: Polyclonal Antibodies. Observed MW: 30kDa. Calculated MW: 4-22kDa
other info2 :
Immunogen: A synthetic peptide of human BCL2L11. Buffer: PBS with 0.02% sodium azide, pH7.3.
products description :
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
ncbi gi num :
323362959
ncbi acc num :
NP_001191035.1
ncbi gb acc num :
NM_001204106.1
uniprot acc num :
O43521
ncbi pathways :
Activation Of BH3-only Proteins Pathway (105658); Activation Of BIM And Translocation To Mitochondria Pathway (105662); Apoptosis Pathway (198797); Apoptosis Pathway (105648); Apoptosis Modulation And Signaling Pathway (198822); B Cell Receptor Signaling Pathway (198909); BDNF Signaling Pathway (712093); BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway (105664); Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); DNA Damage Response (only ATM Dependent) Pathway (198827)
size1 :
0.1 mL
price1 :
275 USD
size2 :
0.2 mL
price2 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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