product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Ciliary neurotrophic factor polyclonal Antibody, HRP conjugated
catalog :
MBS1265068
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1265068
products type :
Antibody
products full name :
Rabbit anti-human Ciliary neurotrophic factor polyclonal Antibody, HRP conjugated
products short name :
Ciliary neurotrophic factor
other names :
ciliary neurotrophic factor; Ciliary neurotrophic factor; ciliary neurotrophic factor; ciliary neurotrophic factor
products gene name :
CNTF
other gene names :
CNTF; CNTF; HCNTF; CNTF
uniprot entry name :
CNTF_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
200
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP
other info2 :
Immunogen: Recombinant human Ciliary neurotrophic factor protein
products description :
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
ncbi gi num :
4758020
ncbi acc num :
NP_000605.1
ncbi gb acc num :
NM_000614.3
uniprot acc num :
P26441
ncbi mol weight :
22,931 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Delta-Notch Signaling Pathway (198879); IL-6-type Cytokine Receptor Ligand Interactions Pathway (1339143); Immune System Pathway (1269170); Interleukin-6 Family Signaling Pathway (1339142); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Signaling By Interleukins Pathway (1269318)
ncbi summary :
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
uniprot summary :
CNTF: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Belongs to the CNTF family. Chromosomal Location of Human Ortholog: 11q12.2. Cellular Component: cytoplasm; extracellular region; extracellular space. Molecular Function: ciliary neurotrophic factor receptor binding; growth factor activity; interleukin-6 receptor binding; protein binding. Biological Process: growth; muscle morphogenesis; negative regulation of neuron apoptosis; negative regulation of photoreceptor cell differentiation; neuron development; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of retinal cell programmed cell death; signal transduction
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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