catalog number :
MBS1265025
products full name :
Rabbit anti-HPV18 Major capsid protein L1 polyclonal Antibody, HRP conjugated
products short name :
HPV18 Major capsid protein L1
other names :
L1 protein; Major capsid protein L1; major capsid L1 protein
other gene names :
L1; L1
uniprot entry name :
VL1_HPV18
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP
other info2 :
Immunogen: Recombinant HPV18 Major capsid protein L1 protein
products description :
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
ncbi acc num :
NP_040317.1
ncbi gb acc num :
NC_001357.1
ncbi mol weight :
63,624 Da