product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Endothelial protein C receptor polyclonal Antibody, Biotin conjugated
catalog :
MBS1265009
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
biotin
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1265009
products type :
Antibody
products full name :
Rabbit anti-human Endothelial protein C receptor polyclonal Antibody, Biotin conjugated
products short name :
Endothelial protein C receptor
products name syn :
Activated protein C receptor; Endothelial cell protein C receptor; CD_antigen=CD201; PROCR; EPCR
other names :
endothelial protein C receptor; Endothelial protein C receptor; endothelial protein C receptor; protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
other gene names :
PROCR; PROCR; CCCA; EPCR; CCD41; EPCR; APC receptor
uniprot entry name :
EPCR_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
238
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA). Not yet tested in other applications.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Biotin
other info2 :
Immunogen: Recombinant human Endothelial protein C receptor protein
products description :
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
ncbi gi num :
34335272
ncbi acc num :
NP_006395.2
ncbi gb acc num :
NM_006404.4
uniprot acc num :
Q9UNN8
ncbi mol weight :
26,671 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (1269373); Common Pathway Of Fibrin Clot Formation (1269371); Formation Of Fibrin Clot (Clotting Cascade) Pathway (1269368); Hemostasis Pathway (1269340)
ncbi summary :
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
uniprot summary :
EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 20q11.2. Cellular Component: cell surface; centrosome; extracellular region; focal adhesion; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; receptor activity. Biological Process: blood coagulation; immune response; leukocyte migration; negative regulation of coagulation
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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