catalog number :
MBS126480
products full name :
FCER1A Polyclonal Antibody
products short name :
[FCER1A]
products name syn :
[FCE1A; FcERI]
other names :
[High affinity immunoglobulin epsilon receptor subunit alpha; High affinity immunoglobulin epsilon receptor subunit alpha; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha]
products gene name :
[FCER1A]
other gene names :
[FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI]
uniprot entry name :
FCERA_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
other info2 :
Immunogen: Recombinant protein of human FCER1A
products categories :
Polyclonal
products description :
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493); Fc Epsilon Receptor (FCERI) Signaling Pathway (833825); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
uniprot summary :
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.