catalog number :
MBS126304
products full name :
PRDX6 Polyclonal Antibody
products short name :
[PRDX6]
products name syn :
[PRDX6; 1-Cys; AOP2; HEL-S-128m; NSGPx; PRX; ai PLA2; p29; peroxiredoxin-6]
other names :
[Peroxiredoxin-6; Peroxiredoxin-6; peroxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm binding protein Li 128m; peroxiredoxin 6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.-); aiPLA2; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase (EC:1.11.1.9); NSGPx; Red blood cells page spot 12]
products gene name :
[PRDX6]
other gene names :
[PRDX6; PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m; AOP2; KIAA0106; 1-Cys PRX; aiPLA2; NSGPx]
uniprot entry name :
PRDX6_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human PRDX6 (NP_004896.1).
products categories :
Polyclonal
products description :
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
ncbi mol weight :
Observed: 27kDa. Calculated: 25kDa
ncbi pathways :
Cellular Responses To Stress Pathway (645258); Detoxification Of Reactive Oxygen Species Pathway (1127552); Metabolic Pathways (132956); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327)
ncbi summary :
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
uniprot summary :
PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily. Protein type: Amino Acid Metabolism - phenylalanine; Oxidoreductase; Energy Metabolism - methane; EC 1.11.1.9; EC 1.11.1.15; Phospholipase. Chromosomal Location of Human Ortholog: 1q25.1. Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol. Molecular Function: antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity. Biological Process: response to reactive oxygen species; phospholipid catabolic process; hydrogen peroxide catabolic process; response to oxidative stress